Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5979
Gene Symbol: RET
RET
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.700 GeneticVariation LHGDN Proteomics study of medullary thyroid carcinomas expressing RET germ-line mutations: identification of new signaling elements. 18756447

2009
Entrez Id: 5979
Gene Symbol: RET
RET
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.700 GeneticVariation LHGDN Incidentally simultaneous occurrence of RET/PTC, H4-PTEN and BRAF mutation in papillary thyroid carcinoma. 18226854

2008
Entrez Id: 5979
Gene Symbol: RET
RET
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.700 GeneticVariation LHGDN A new germline point mutation in Ret exon 8 (cys515ser) in a family with medullary thyroid carcinoma. 18631007

2008
Entrez Id: 5979
Gene Symbol: RET
RET
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.700 Biomarker LHGDN Here, we show that nuclear localization of beta-catenin is frequent in both thyroid tumors and their metastases from MEN 2 patients, suggesting a novel mechanism of RET-mediated function through the beta-catenin signaling pathway. 18316596

2008
Entrez Id: 5979
Gene Symbol: RET
RET
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.700 Biomarker LHGDN Synergistic effect of oncogenic RET and loss of p18 on medullary thyroid carcinoma development. 18316595

2008
Entrez Id: 5979
Gene Symbol: RET
RET
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.700 Biomarker LHGDN Molecular mechanisms of medullary thyroid carcinoma: current approaches in diagnosis and treatment. 17952863

2008
Entrez Id: 5979
Gene Symbol: RET
RET
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.700 GeneticVariation LHGDN High resolution array-comparative genomic hybridization profiling reveals deoxyribonucleic acid copy number alterations associated with medullary thyroid carcinoma. 18765511

2008
Entrez Id: 5979
Gene Symbol: RET
RET
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.700 GeneticVariation LHGDN Diffuse sclerosing variant of papillary thyroid carcinoma: lack of BRAF mutation but occurrence of RET/PTC rearrangements. 17464312

2007
Entrez Id: 5979
Gene Symbol: RET
RET
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.700 Biomarker LHGDN In conclusion, we found RET amplification, which is a rare oncogenic aberration, in thyroid cancer. 17270245

2007
Entrez Id: 5979
Gene Symbol: RET
RET
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.700 GeneticVariation LHGDN Fine-needle aspiration molecular analysis for the diagnosis of papillary thyroid carcinoma through BRAF V600E mutation and RET/PTC rearrangement. 17727338

2007
Entrez Id: 5979
Gene Symbol: RET
RET
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.700 AlteredExpression LHGDN High prevalence of RET, RAS, and ERK expression in Hashimoto's thyroiditis and in papillary thyroid carcinoma in the Korean population. 17900235

2007
Entrez Id: 5979
Gene Symbol: RET
RET
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.700 GeneticVariation LHGDN A break-apart fluorescence in situ hybridization assay for detecting RET translocations in papillary thyroid carcinoma. 17954268

2007
Entrez Id: 5979
Gene Symbol: RET
RET
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.700 GeneticVariation LHGDN The occurrence and the type of germline mutations in the RET gene in patients with medullary thyroid carcinoma and their unaffected kindred's from Central Poland. 18058472

2007
Entrez Id: 5979
Gene Symbol: RET
RET
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.700 GeneticVariation LHGDN RET genetic screening in patients with medullary thyroid cancer and their relatives: experience with 807 individuals at one center. 17895320

2007
Entrez Id: 5979
Gene Symbol: RET
RET
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.700 GeneticVariation LHGDN Significance of the RET proto-oncogene polymorphisms in Turkish sporadic medullary thyroid carcinoma patients. 17185892

2006
Entrez Id: 5979
Gene Symbol: RET
RET
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.700 GeneticVariation LHGDN Molecular analysis of the RET and NTRK1 gene rearrangements in papillary thyroid carcinoma in the Polish population. 16483615

2006
Entrez Id: 5979
Gene Symbol: RET
RET
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.700 GeneticVariation LHGDN Germline RET mutations in exons 10 and 11: an Iranian survey of 57 medullary thyroid carcinoma cases. 17623957

2006
Entrez Id: 5979
Gene Symbol: RET
RET
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.700 GeneticVariation LHGDN An in-frame complex germline mutation in the juxtamembrane intracellular domain causing RET activation in familial medullary thyroid carcinoma. 16954442

2006
Entrez Id: 5979
Gene Symbol: RET
RET
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.700 GeneticVariation LHGDN Clinical case seminar: in vivo and in vitro characterization of a novel germline RET mutation associated with low-penetrant nonaggressive familial medullary thyroid carcinoma. 16384843

2006
Entrez Id: 5979
Gene Symbol: RET
RET
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.700 GeneticVariation LHGDN [Characterization of RET proto-oncogene C634Y mutation in a Moroccan family with multiple endocrine neoplasia type 2A]. 16596053

2006
Entrez Id: 5979
Gene Symbol: RET
RET
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.700 GeneticVariation LHGDN Medullary thyroid carcinoma in a child with a new RET mutation and a RET polymorphism. 15844786

2005
Entrez Id: 5979
Gene Symbol: RET
RET
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.700 GeneticVariation LHGDN Germline homozygous mutations at codon 804 in the RET protooncogene in medullary thyroid carcinoma/multiple endocrine neoplasia type 2A patients. 15741265

2005
Entrez Id: 5979
Gene Symbol: RET
RET
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.700 GeneticVariation LHGDN Exon 5 of the RET proto-oncogene: a newly detected risk exon for familial medullary thyroid carcinoma, a novel germ-line mutation Gly321Arg. 16419493

2005
Entrez Id: 5979
Gene Symbol: RET
RET
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.700 Biomarker LHGDN RET/PTC and CK19 expression in papillary thyroid carcinoma and its clinicopathologic correlation. 15716612

2005
Entrez Id: 5979
Gene Symbol: RET
RET
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.700 GeneticVariation LHGDN [RET mutations and preventive treatment of medullary thyroid cancer]. 15988377

2005