Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2796
Gene Symbol: GNRH1
GNRH1
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.080 Biomarker LHGDN Instead, in ovarian cancer cells, GnRH receptors appear to couple to the pertussis toxin-sensitive protein G(alpha i), leading to the activation of protein phosphatase, which in turn interferes with growth factor-induced mitogenic signals. 18959739

2008
Entrez Id: 2796
Gene Symbol: GNRH1
GNRH1
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.080 Biomarker LHGDN Gonadotropin-releasing hormone retards doxorubicin-induced apoptosis and serine/threonine phosphatase inhibition in ovarian cancer cells. 15809743

2005
Entrez Id: 2796
Gene Symbol: GNRH1
GNRH1
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.080 Biomarker LHGDN In previous studies we have demonstrated that in ovarian cancer cell lines except for the EFO-27 cell line GnRH-I antagonist Cetrorelix has comparable antiproliferative effects as GnRH-I agonists indicating that the dichotomy of GnRH-I agonists and antagonists might not apply to the GnRH-I system in cancer cells. 14594454

2003