Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 GeneticVariation LHGDN Active and passive smoking, IL6, ESR1, and breast cancer risk. 17594514

2008
Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 GeneticVariation LHGDN Modifying effects of IL-6 polymorphisms on body size-associated breast cancer risk. 18239642

2008
Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 AlteredExpression LHGDN Interestingly, mice coinjected with MCF-7 breast tumor cells and senescent skin fibroblasts, which secrete IL-6, developed tumors, whereas mice coinjected with presenescent skin fibroblasts that produce little to no IL-6 failed to form xenograft tumors. 18974155

2008
Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 PosttranslationalModification LHGDN We examined IL-6 levels in primary breast tumors and found a positive correlation between pStat3 and IL-6 expression. 17531096

2007
Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 GeneticVariation LHGDN Association of breast cancer and cytokine gene polymorphism in Turkish women. 17965799

2007
Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 AlteredExpression LHGDN Prognostic value of serum level of interleukin-6 and interleukin-8 in metastatic breast cancer patients. 18689272

2006
Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 AlteredExpression LHGDN Interleukin-6, multidrug resistance protein-1 expression and response to paclitaxel in women with metastatic breast cancer: results of cancer and leukemia group B trial 159806. 16773437

2006
Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 GeneticVariation LHGDN Interleukin-1 and interleukin-6 gene polymorphisms and the risk of breast cancer in caucasian women. 16115908

2005
Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 GeneticVariation LHGDN The interleukin-6 gene: a susceptibility factor that may contribute to racial and ethnic disparities in breast cancer mortality. 15609131

2004
Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 AlteredExpression LHGDN Prognostic value of serum levels of interleukin 6 and of serum and plasma levels of vascular endothelial growth factor in hormone-refractory metastatic breast cancer patients. 12771987

2003
Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 Biomarker LHGDN Autocrine production of interleukin 6 causes multidrug resistance in breast cancer cells. 11751408

2001