Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3952
Gene Symbol: LEP
LEP
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 AlteredExpression LHGDN Mechanism of leptin expression in breast cancer cells: role of hypoxia-inducible factor-1alpha. 17653093

2008
Entrez Id: 3952
Gene Symbol: LEP
LEP
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 AlteredExpression LHGDN leptin-induced growth stimulation of breast cancer cells involves recruitment of histone acetyltransferases and mediator complex to CYCLIN D1 promoter via activation of Stat3. 17344214

2007
Entrez Id: 3952
Gene Symbol: LEP
LEP
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 AlteredExpression LHGDN Messenger RNA expression of leptin and leptin receptors and their prognostic value in 322 human primary breast cancers. 16609020

2006
Entrez Id: 3952
Gene Symbol: LEP
LEP
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 AlteredExpression LHGDN Increased expression of leptin and the leptin receptor as a marker of breast cancer progression: possible role of obesity-related stimuli. 16533767

2006
Entrez Id: 3952
Gene Symbol: LEP
LEP
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 AlteredExpression LHGDN Leptin: a proliferative factor for breast cancer? Study on human ductal carcinoma. 16009333

2005
Entrez Id: 3952
Gene Symbol: LEP
LEP
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 Biomarker LHGDN Enhanced expression of leptin and leptin receptor (OB-R) in human breast cancer. 15240518

2004
Entrez Id: 3952
Gene Symbol: LEP
LEP
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 AlteredExpression LHGDN Serum leptin, prolactin and vascular endothelial growth factor (VEGF) levels in patients with breast cancer. 12687277

2003
Entrez Id: 3952
Gene Symbol: LEP
LEP
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 AlteredExpression LHGDN Leptin enhances, via AP-1, expression of aromatase in the MCF-7 cell line. 12734209

2003
Entrez Id: 3952
Gene Symbol: LEP
LEP
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 Biomarker LHGDN Leptin mediates a proliferative response in human MCF7 breast cancer cells. 12054648

2002