Source: MGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1139
Gene Symbol: CHRNA7
CHRNA7
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.700 Biomarker MGD In humans microdeletion of the CHRNA7 (α7 nicotinic acetylcholine receptor, nAChR) gene is associated with cortical dysfunction in a broad spectrum of neurodevelopmental and neuropsychiatric disorders including schizophrenia while in mice similar deletion causes analogous abnormalities including impaired attention, working-memory and learning. 24983521

2014
Entrez Id: 1139
Gene Symbol: CHRNA7
CHRNA7
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.700 Biomarker MGD Olfactory discrimination varies in mice with different levels of α7-nicotinic acetylcholine receptor expression. 20713028

2010
Entrez Id: 1139
Gene Symbol: CHRNA7
CHRNA7
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.700 Biomarker MGD This suggests a role for the alpha7 subunit in working/episodic memory and a potential role for the alpha7 neural nicotinic receptor gene (CHRNA7) in schizophrenia and its endophenotypes. 16923147

2006
Entrez Id: 1139
Gene Symbol: CHRNA7
CHRNA7
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.700 Biomarker MGD Mice deficient in CHRNA7, a subunit of the nicotinic acetylcholine receptor, produce sperm with impaired motility. 15944242

2005
Entrez Id: 1139
Gene Symbol: CHRNA7
CHRNA7
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.700 Biomarker MGD A phenotype for the alpha 7 nicotinic acetylcholine receptor null mutant. 15364017

2004