Source: ORPHANET

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3654
Gene Symbol: IRAK1
IRAK1
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		0.500 SusceptibilityMutation ORPHANET These data suggest contributions of both IRAK1 and MECP2 to SLE susceptibility. 22904263

2013
Entrez Id: 3654
Gene Symbol: IRAK1
IRAK1
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		0.500 SusceptibilityMutation ORPHANET Our data demonstrate that the polymorphisms rs3027898 and rs1059702 of IRAK1 gene are associated with SLE in the Chinese Han population. 23435933

2013
Entrez Id: 3654
Gene Symbol: IRAK1
IRAK1
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		0.500 SusceptibilityMutation ORPHANET Genetics and epigenetics of systemic lupus erythematosus. 23943494

2013
Entrez Id: 3654
Gene Symbol: IRAK1
IRAK1
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		0.500 SusceptibilityMutation ORPHANET Role of cytokines in systemic lupus erythematosus: recent progress from GWAS and sequencing. 22654485

2012
Entrez Id: 3654
Gene Symbol: IRAK1
IRAK1
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		0.500 SusceptibilityMutation ORPHANET Recent insights into the genetic basis of systemic lupus erythematosus. 19440199

2009
Entrez Id: 3654
Gene Symbol: IRAK1
IRAK1
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		0.500 SusceptibilityMutation ORPHANET Family-based TDT showed a significant association of SLE with a N673S polymorphism in the P-selectin gene (SELP) (P = 5.74 x 10(-6)) and a C203S polymorphism in the interleukin-1 receptor-associated kinase 1 gene (IRAK1) (P = 9.58 x 10(-6)). 18050247

2007