Source: ORPHANET

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4204
Gene Symbol: MECP2
MECP2
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		0.500 SusceptibilityMutation ORPHANET These data suggest contributions of both IRAK1 and MECP2 to SLE susceptibility. 22904263

2013
Entrez Id: 4204
Gene Symbol: MECP2
MECP2
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		0.500 SusceptibilityMutation ORPHANET Our data suggest that the lupus-associated variant in the MECP2/IRAK1 locus has the potential to affect all 3 epigenetic mechanisms: DNA methylation, microRNA expression, and histone modification. 23428850

2013
Entrez Id: 4204
Gene Symbol: MECP2
MECP2
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		0.500 SusceptibilityMutation ORPHANET Mutations of SNPs (rs2075596, rs2239464) of MeCP2 showed increased risk of developing SLE. 23857988

2013
Entrez Id: 4204
Gene Symbol: MECP2
MECP2
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		0.500 SusceptibilityMutation ORPHANET Role of cytokines in systemic lupus erythematosus: recent progress from GWAS and sequencing. 22654485

2012
Entrez Id: 4204
Gene Symbol: MECP2
MECP2
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		0.500 SusceptibilityMutation ORPHANET Recent insights into the genetic basis of systemic lupus erythematosus. 19440199

2009