Source: ORPHANET

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7128
Gene Symbol: TNFAIP3
TNFAIP3
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		0.700 SusceptibilityMutation ORPHANET Variants in TNFSF4, TNFAIP3, TNIP1, BLK, SLC15A4 and UBE2L3 interact to confer risk of systemic lupus erythematosus in Chinese population. 24091983

2014
Entrez Id: 7128
Gene Symbol: TNFAIP3
TNFAIP3
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		0.700 SusceptibilityMutation ORPHANET An enhancer element harboring variants associated with systemic lupus erythematosus engages the TNFAIP3 promoter to influence A20 expression. 24039598

2013
Entrez Id: 7128
Gene Symbol: TNFAIP3
TNFAIP3
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		0.700 SusceptibilityMutation ORPHANET Genetics and epigenetics of systemic lupus erythematosus. 23943494

2013
Entrez Id: 7128
Gene Symbol: TNFAIP3
TNFAIP3
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		0.700 SusceptibilityMutation ORPHANET Role of cytokines in systemic lupus erythematosus: recent progress from GWAS and sequencing. 22654485

2012
Entrez Id: 7128
Gene Symbol: TNFAIP3
TNFAIP3
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		0.700 SusceptibilityMutation ORPHANET These results establish this TT>A variant as the most likely functional polymorphism responsible for the association between TNFAIP3 and SLE. 21336280

2011
Entrez Id: 7128
Gene Symbol: TNFAIP3
TNFAIP3
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		0.700 SusceptibilityMutation ORPHANET These results indicated that TNFAIP3 is a susceptibility gene to SLE both in the Caucasian and Asian populations. 20617138

2010