Source: PSYGENET

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3952
Gene Symbol: LEP
LEP
CUI: C0011570
Disease: Mental Depression
Mental Depression 		0.400 Biomarker PSYGENET Is there a role for leptin in the reduction of depression symptoms during weight loss therapy in obese adolescent girls and boys? 25629253

2015
Entrez Id: 3952
Gene Symbol: LEP
LEP
CUI: C0011570
Disease: Mental Depression
Mental Depression 		0.400 Biomarker PSYGENET Our results suggest an involvement of leptin in antidepressant action and cognitive function in depression with genetic polymorphisms in the leptin gene, decreased leptin gene expression and leptin deficiency in serum being risk factors for resistance to antidepressant therapy in depressed patients. 23026132

2013
Entrez Id: 3952
Gene Symbol: LEP
LEP
CUI: C0011570
Disease: Mental Depression
Mental Depression 		0.400 Biomarker PSYGENET Selective deletion of leptin receptors in adult hippocampus induces depression-related behaviours. 22932068

2013
Entrez Id: 3952
Gene Symbol: LEP
LEP
CUI: C0011570
Disease: Mental Depression
Mental Depression 		0.400 Biomarker PSYGENET Expression of mutant huntingtin in leptin receptor-expressing neurons does not control the metabolic and psychiatric phenotype of the BACHD mouse. 23251447

2012
Entrez Id: 3952
Gene Symbol: LEP
LEP
CUI: C0011570
Disease: Mental Depression
Mental Depression 		0.400 Biomarker PSYGENET Forebrain glutamatergic neurons mediate leptin action on depression-like behaviors and synaptic depression. 22408745

2012