Source: PSYGENET

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5173
Gene Symbol: PDYN
PDYN
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.330 Biomarker PSYGENET Virus-mediated shRNA knockdown of prodynorphin in the rat nucleus accumbens attenuates depression-like behavior and cocaine locomotor sensitization. 24816773

2014
Entrez Id: 5173
Gene Symbol: PDYN
PDYN
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.330 Biomarker PSYGENET A trend for association between depression severity and PDYN variation was detected. 23101464

2013
Entrez Id: 5173
Gene Symbol: PDYN
PDYN
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.330 Biomarker PSYGENET Knockdown of prodynorphin gene prevents cognitive decline, reduces anxiety, and rescues loss of group 1 metabotropic glutamate receptor function in aging. 23904614

2013
Entrez Id: 5173
Gene Symbol: PDYN
PDYN
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.330 Biomarker PSYGENET Roles of nucleus accumbens CREB and dynorphin in dysregulation of motivation. 23293139

2013
Entrez Id: 5173
Gene Symbol: PDYN
PDYN
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.330 Biomarker PSYGENET Impaired periamygdaloid-cortex prodynorphin is characteristic of opiate addiction and depression. 24231353

2013