DisGeNET - a database of gene-disease associations

Source: PSYGENET

Disease: Psychotic Disorders ×

Gene: DGCR8 ×

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Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	54487
Gene Symbol:	DGCR8

DGCR8

CUI:	C0033975
Disease:	Psychotic Disorders

Psychotic Disorders

0.300

Biomarker

PSYGENET

This suggests that Dgcr8-microRNA-Drd2-dependent thalamocortical disruption is a pathogenic event underlying schizophrenia-associated psychosis.

2014