Source: PSYGENET

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3361
Gene Symbol: HTR5A
HTR5A
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.360 Biomarker PSYGENET These results collectively suggest that ASP5736 is a novel and potent 5-HT5A receptor antagonist that not only ameliorates positive-like symptoms but also cognitive impairments in animal models of schizophrenia, without adverse effects. 25108314

2014
Entrez Id: 3361
Gene Symbol: HTR5A
HTR5A
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.360 Biomarker PSYGENET These data provided convergent evidence for a significant role of the 5-HT(5A) gene in schizophrenia and more specifically in patients with later age at onset. 15203288

2004
Entrez Id: 3361
Gene Symbol: HTR5A
HTR5A
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.360 Biomarker PSYGENET Association of a 5-HT(5A) receptor polymorphism, Pro15Ser, to schizophrenia. 11317225

2001
Entrez Id: 3361
Gene Symbol: HTR5A
HTR5A
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.360 Biomarker PSYGENET We conclude that allelic variation in the human 5-HT5A receptor gene may be involved in susceptibility to schizophrenia and affective disorders but not in determining response to clozapine. 10884063

2000