Source: PSYGENET

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6558
Gene Symbol: SLC12A2
SLC12A2
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.370 Biomarker PSYGENET Together, these preclinical and clinical results suggest that variation in NKCC1 may increase risk for schizophrenia via alterations of mRNA expression at the molecular level and impairment of optimal prefrontal function at the macro or systems level. 24695712

2014
Entrez Id: 6558
Gene Symbol: SLC12A2
SLC12A2
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.370 Biomarker PSYGENET This study shows that two SNPs in intergenic of the CTXN3 and SLC12A2 genes, rs245178 and rs698172, are associated with risk of schizophrenia in Thai population. 22643131

2012
Entrez Id: 6558
Gene Symbol: SLC12A2
SLC12A2
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.370 Biomarker PSYGENET Furthermore, DISC1 and NKCC1 interact epistatically to affect risk for schizophrenia in two independent case control studies. 22385968

2012
Entrez Id: 6558
Gene Symbol: SLC12A2
SLC12A2
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.370 Biomarker PSYGENET To compare the levels of NKCC1, KCC2, OXSR1, STK39, WNK1, WNK3, and WNK4 transcripts in prefrontal cortex area 9 between subjects with schizophrenia and healthy comparison subjects. 20819979

2011