Source: PSYGENET

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 84062
Gene Symbol: DTNBP1
DTNBP1
CUI: C0270458
Disease: Severe major depression with psychotic features
Severe major depression with psychotic features 		0.330 Biomarker PSYGENET Pharmacogenetic studies implicate 5-HTT, TPH1, and DTNBP1 gene variation in the mediation of antidepressant treatment response in psychotic depression. 23512949

2013
Entrez Id: 84062
Gene Symbol: DTNBP1
DTNBP1
CUI: C0270458
Disease: Severe major depression with psychotic features
Severe major depression with psychotic features 		0.330 Biomarker PSYGENET In summary, the present results provide preliminary support for dysbindin (DTNBP1) gene variation, particularly SNPs rs1997679 and rs9370822, to be associated with the clinical phenotype of psychotic depression suggesting a possible neurobiological mechanism for an intermediate trait on the continuum between affective disorders and schizophrenia. 20951386

2011