Source: PSYGENET

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 153
Gene Symbol: ADRB1
ADRB1
CUI: C0525045
Disease: Mood Disorders
Mood Disorders 		0.310 Biomarker PSYGENET Further, several genome scans for mood disorders, both unipolar and bipolar, have indicated linkage to the chromosomal regions of 5q23-q33.3, 8p12-p11.2, 4p16, and 10q24-q26, the location of the adrenergic receptors alpha1B (ADRA1B), beta3 (ADRB3), alpha2C (ADRA2C), alpha2A (ADRA2A), and beta1 (ADRB1). 16526032

2006
Entrez Id: 153
Gene Symbol: ADRB1
ADRB1
CUI: C0525045
Disease: Mood Disorders
Mood Disorders 		0.310 Biomarker PSYGENET A recently identified functional polymorphism in the beta(1)-adrenergic receptor (G1165C) leading to the amino acid variation Gly389Arg was associated with an enhanced coupling to the stimulatory G(s)-protein and increased adenylyl cyclase activation, disturbances which are often observed in affective disorders. 12815745

2003