DisGeNET - a database of gene-disease associations

Source: PSYGENET

Disease: Mood Disorders ×

Gene: HTR6 ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	3362
Gene Symbol:	HTR6

HTR6

CUI:	C0525045
Disease:	Mood Disorders

Mood Disorders

0.320

Biomarker

PSYGENET

Several evidence suggests that alterations in serotonin 6 (5-HT6) receptors might be associated with the pathophysiology of mood disorders.

20394784

2010

Entrez Id:	3362
Gene Symbol:	HTR6

HTR6

CUI:	C0525045
Disease:	Mood Disorders

Mood Disorders

0.320

Biomarker

PSYGENET

The serotonin 5-HT(6) receptor has become a promising target for the treatment of neuropsychological diseases, such as affective disorders.

18206183

2008

Entrez Id:	3362
Gene Symbol:	HTR6

HTR6

CUI:	C0525045
Disease:	Mood Disorders

Mood Disorders

0.320

Biomarker

PSYGENET

We genotyped the 5-HT(6) receptor in 139 patients with mood disorders and 147 controls.

10581475

1999