Source: PSYGENET

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0525045
Disease: Mood Disorders
Mood Disorders 		0.370 Biomarker PSYGENET A whole genome expression analysis of peripheral blood mononuclear cells yielded 12 protein-coding genes (ADM, APBB3, CD160, CFD, CITED2, CTSZ, IER5, NFKBIZ, NR4A2, NUCKS1, SERTAD1, TNF) that were differentially expressed between 29 unmedicated depressed patients with a mood disorder (8 bipolar disorder, 21 major depressive disorder) and 24 healthy controls (HCs). 23064081

2013
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0525045
Disease: Mood Disorders
Mood Disorders 		0.370 Biomarker PSYGENET Tumor necrosis factor-alpha has been investigated as a potential molecular target in mood disorders. 19175760

2009
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0525045
Disease: Mood Disorders
Mood Disorders 		0.370 Biomarker PSYGENET The present study does not support the involvement of the TNF, IL1A, IL1B, IL6, IL1RN and IL10 variants as major genetic risk factors contributing to early-onset mood disorders. 18832862

2008
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0525045
Disease: Mood Disorders
Mood Disorders 		0.370 Biomarker PSYGENET However, variation at other polymorphisms within TNFalpha or in other oestrogen-regulated genes involved in immune function remain interesting candidates for study in post-partum mood disorders. 11324946

2000