DisGeNET - a database of gene-disease associations

Source: RGD

Disease: Intracranial Aneurysm ×

Gene: MMP9 ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	4318
Gene Symbol:	MMP9

MMP9

CUI:	C0007766
Disease:	Intracranial Aneurysm

Intracranial Aneurysm

0.270

Biomarker

RGD

T1DM increases IA formation.The increased RAGE, MMP9 and TLR4 expressions might contribute to IA formation in T1DM rats.

23844137

2013

Entrez Id:	4318
Gene Symbol:	MMP9

MMP9

CUI:	C0007766
Disease:	Intracranial Aneurysm

Intracranial Aneurysm

0.270

Therapeutic

RGD

Imidapril inhibits cerebral aneurysm formation in an angiotensin-converting enzyme-independent and matrix metalloproteinase-9-dependent manner.

21937941

2012

Entrez Id:	4318
Gene Symbol:	MMP9

MMP9

CUI:	C0007766
Disease:	Intracranial Aneurysm

Intracranial Aneurysm

0.270

Biomarker

RGD

Macrophage-derived matrix metalloproteinase-2 and -9 promote the progression of cerebral aneurysms in rats.

17122420

2007

Entrez Id:	4318
Gene Symbol:	MMP9

MMP9

CUI:	C0007766
Disease:	Intracranial Aneurysm

Intracranial Aneurysm

0.270

Biomarker

RGD

Role of TIMP-1 and TIMP-2 in the progression of cerebral aneurysms.

17569872

2007