Source: RGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 842
Gene Symbol: CASP9
CASP9
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy 		0.210 Therapeutic RGD In the dual-luciferase reporter assay, TKL significantly inhibited luciferase activity in cells co-transfected with p65 and a wild-type capase-9 construct instead of mutated caspase-9 constructs.Taken together, our results show that TKL helps to protect against DN by inhibiting the LOX1/NF-κB/caspase-9 signaling pathway, suggesting TKL as a promising agent for treating DN. 30038056

2018
Entrez Id: 842
Gene Symbol: CASP9
CASP9
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy 		0.210 Therapeutic RGD Renoprotective effect of nifuroxazide in diabetes-induced nephropathy: impact on NFκB, oxidative stress, and apoptosis. 29606028

2018