Source: RGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.600 Therapeutic RGD We hypothesized that inhibition of angiotensin-converting enzyme (ACE) in the hypothalamic paraventricular nucleus (PVN) attenuates angiotensin II (ANG II)-induced hypertension via restoring neurotransmitters and cytokines. 24342267

2014
Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.600 Biomarker RGD Therefore, research to find and develop safer, effective and economical ACE inhibitors is necessary for the prevention and remedy of hypertension. 17392119

2007
Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.600 Biomarker RGD Hence, we first investigated the tissue distribution of ACE2 and ACE in the rat and then whether hypertension programming differentially affects both enzymes. 16203874

2005
Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.600 Therapeutic RGD Tissue levels, tissue angiotensin converting enzyme inhibition and antihypertensive effect of the novel antihypertensive agent alacepril in renal hypertensive rats. 3006710

1986