Source: RGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.250 Biomarker RGD We observed that: (1) intracerebral ventricular injection of (ICV) IL-1beta induced pressor responses; (2) hypertension induced by IL-1beta was blocked by ICV an IL-1 antagonist, IL-1ra; (3) ICV IL-1ra attenuated the pressor response induced by FS but intravenous injection of IL-1ra did not significantly reduce this response; (4) the hypertensive response to conditioned fear stimuli was reversed by ICV IL-1ra; (5) FS-induced-analgesia was attenuated by ICV IL-1ra and this effect disappeared 15 min after ICV IL-1ra. 11585563

2001