DisGeNET - a database of gene-disease associations

Source: RGD

Disease: Hepatoblastoma ×

Gene: INSR ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	3643
Gene Symbol:	INSR

INSR

CUI:	C0206624
Disease:	Hepatoblastoma

Hepatoblastoma

0.220

Biomarker

RGD

The beta secretase BACE1 regulates the expression of insulin receptor in the liver.

29610518

2018

Entrez Id:	3643
Gene Symbol:	INSR

INSR

CUI:	C0206624
Disease:	Hepatoblastoma

Hepatoblastoma

0.220

Biomarker

RGD

Mitogenic insulin receptor-A is overexpressed in human hepatocellular carcinoma due to EGFR-mediated dysregulation of RNA splicing factors.

23633480

2013