×
Entrez Id:
7422
Gene Symbol:
VEGFA
VEGFA
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
Vascular endothelial growth factor gene polymorphisms and colorectal cancer risk: a meta-analysis.
22058001
2011
×
Entrez Id:
7422
Gene Symbol:
VEGFA
VEGFA
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
Association of VEGF and KDR single nucleotide polymorphisms with colorectal cancer susceptibility in Koreans.
23169005
2013
×
Entrez Id:
7422
Gene Symbol:
VEGFA
VEGFA
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
Overall, while the genetic variations in the VEGF and MMP genes are attractive candidates as prognostic markers, our study showed no evidence of associations of a large set of SNPs in these genes and overall survival of colorectal cancer patients in our study.
27334288
2016
×
Entrez Id:
7422
Gene Symbol:
VEGFA
VEGFA
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
Association between EGF, TGF-beta1, VEGF gene polymorphism and colorectal cancer .
19011936
2009
×
Entrez Id:
7422
Gene Symbol:
VEGFA
VEGFA
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
Synergy of Ginkgetin and Resveratrol in Suppressing VEGF -Induced Angiogenesis: A Therapy in Treating Colorectal Cancer .
31757048
2019
×
Entrez Id:
7422
Gene Symbol:
VEGFA
VEGFA
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
Vascular endothelial growth factor (VEGF ) gene polymorphisms and colorectal cancer : a meta-analysis of epidemiologic studies.
23005896
2012
×
Entrez Id:
7422
Gene Symbol:
VEGFA
VEGFA
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
VEGFA gene locus (6p12) amplification identifies a small but highly aggressive subgroup of colorectal cancer [corrected] patients.
21743435
2011
×
Entrez Id:
7422
Gene Symbol:
VEGFA
VEGFA
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
Clinical implications of genetic variations in the VEGF system in relation to colorectal cancer .
22118052
2011
×
Entrez Id:
7422
Gene Symbol:
VEGFA
VEGFA
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
The aim of this study was to investigate the association between the risk for colorectal cancer and single nucleotide polymorphisms (SNP) of matrix metalloproteinase-2 (MMP2) -1306C/T , vascular endothelial growth factor (VEGF ) 936C/T and hypoxia inducible factor-1α (HIF1A) 1772C/T .
21378341
2011
×
Entrez Id:
7422
Gene Symbol:
VEGFA
VEGFA
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
Prognostic significance of vascular endothelial growth factor gene polymorphisms in patients with colorectal cancer .
23132736
2013
×
Entrez Id:
7422
Gene Symbol:
VEGFA
VEGFA
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
Interplay between 3'-UTR polymorphisms in the vascular endothelial growth factor (VEGF ) gene and metabolic syndrome in determining the risk of colorectal cancer in Koreans.
25423914
2014
×
Entrez Id:
7422
Gene Symbol:
VEGFA
VEGFA
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
Association of vascular endothelial growth factor gene polymorphisms with susceptibility and clinicopathologic characteristics of colorectal cancer .
18583877
2008
×
Entrez Id:
7422
Gene Symbol:
VEGFA
VEGFA
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
Angiogenic and Antiangiogenic VEGFA Splice Variants in Colorectal Cancer : Prospective Retrospective Cohort Study in Patients Treated With Irinotecan-Based Chemotherapy and Bevacizumab.
31402291
2019
×
Entrez Id:
7422
Gene Symbol:
VEGFA
VEGFA
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
VEGF gene polymorphisms and susceptibility to colorectal cancer .
25635747
2015
×
Entrez Id:
7422
Gene Symbol:
VEGFA
VEGFA
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
Association between Polymorphisms in Vascular Endothelial Growth Factor Gene and Response to Chemotherapies in Colorectal Cancer : A Meta-Analysis.
25955730
2015
×
Entrez Id:
7422
Gene Symbol:
VEGFA
VEGFA
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
Furthermore, the subgroup analysis of recessive model indicates that VEGF +405G/C polymorphisms increase the risk for colorectal cancer .
24474253
2014
×
Entrez Id:
7422
Gene Symbol:
VEGFA
VEGFA
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
The present study suggests that the VEGF gene polymorphisms may play a role in the development of colorectal cancer .
18830612
2009
×
Entrez Id:
7422
Gene Symbol:
VEGFA
VEGFA
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
Our meta-analysis indicated that VEGF -2578C/A polymorphism was associated with the risk of colorectal cancer under homozygote comparison (OR=0.70, 95% CI=0.53-0.92), dominant model (OR=0.72, 95% CI=0.57-0.92), and recessive model (OR=0.82, 95% CI=0.67-1.01), although no evidence of association between VEGF -2578C/A polymorphism and cancer risk was observed as we compared in the pooled analyses (homozygote comparison: OR=0.97, 95% CI=0.81-1.16).
20635170
2011
×
Entrez Id:
7422
Gene Symbol:
VEGFA
VEGFA
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
Vascular endothelial growth factor gene polymorphisms in patients with colorectal cancer .
20187681
2010
×
Entrez Id:
7422
Gene Symbol:
VEGFA
VEGFA
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
KRAS and VEGF gene 3'-UTR single nucleotide polymorphisms predicted susceptibility in colorectal cancer .
28328959
2017
×
Entrez Id:
7422
Gene Symbol:
VEGFA
VEGFA
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
The importance of -460 C/T and +405 G/C single nucleotide polymorphisms to the function of vascular endothelial growth factor A in colorectal cancer .
19904558
2010
×
Entrez Id:
7422
Gene Symbol:
VEGFA
VEGFA
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
VEGF isoforms and mutations in human colorectal cancer .
12209585
2002
×
Entrez Id:
7422
Gene Symbol:
VEGFA
VEGFA
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
We analyzed VEGF (-2578C>A, -1498C>T, -1154G>A, -634C>G, +936C>T) and eNOS (+894G>T, -786T>C, VNTR (variable number of tandem repeats) 27bp intron 4) polymorphisms by direct sequencing or Real Time PCR in 237 patients with advanced colorectal cancer .
25079441
2014
×
Entrez Id:
7422
Gene Symbol:
VEGFA
VEGFA
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
Biology and therapeutic implications of VEGF-A splice isoforms and single-nucleotide polymorphisms in colorectal cancer .
27943279
2017
×
Entrez Id:
7422
Gene Symbol:
VEGFA
VEGFA
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
VEGF gene polymorphisms were found to be an independent prognostic marker for patients with colorectal cancer .
18172253
2008