Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE Preoperative neutrophil-lymphocyte ratio and CEA is associated with poor prognosis in patients with synchronous colorectal cancer liver metastasis. 30941323

2019

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE Quantification of colorectal cancer micrometastases in lymph nodes by nested and real-time reverse transcriptase-PCR analysis for carcinoembryonic antigen. 15355906

2004

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE Effects of vitamin D and omega-3 fatty acids co-supplementation on inflammatory biomarkers, tumor marker CEA, and nutritional status in patients with colorectal cancer: a study protocol for a double blind randomized controlled trial. 31815661

2019

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE To examine overall mortality, colorectal cancer-specific mortality, and colorectal cancer-specific recurrence rates among patients with stage II or III colorectal cancer who were randomized after curative surgery to 2 alternative schedules for follow-up testing with computed tomography and carcinoembryonic antigen. 29800179

2018

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE Carcinoembryonic antigen directed PET-CECT scanning for postoperative surveillance of colorectal cancer. 28444968

2017

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE Application and Indication of Carcinoembryonic Antigen Triggered 18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Scanning in the Detection of Relapse of Colorectal Cancer Patients After Curative Therapy. 28481810

2017

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 AlteredExpression BEFREE The aim of this study was to assess the prognostic value of carcinoembryonic antigen (CEA) messenger RNA (mRNA) detection in peripheral blood samples from patients with colorectal cancer. 11266372

2001

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 AlteredExpression BEFREE Interferon alpha enhances expression of TAG-72 and carcinoembryonic antigen in patients with primary colorectal cancer. 7600563

1995

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 AlteredExpression BEFREE Since carcinoembryonic antigen (CEA; CEACAM5) is abundantly overexpressed in colorectal cancer, it is a potential target for tPDT of colorectal cancer. 31828541

2019

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 AlteredExpression BEFREE Multiple molecular markers as predictors of colorectal cancer in patients with normal perioperative serum carcinoembryonic antigen levels. 17406027

2007

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE Serum sAPRIL had a positive correlation with CEA (r=0.637, P=0.000) and CA19-9 (r=0.357, P=0.008) in 35 patients with colorectal cancer. sAPRIL showed higher sensitivity (82.9%) than those of CEA (74.3%) and CA19-9 (65.7%) in CRC, respectively. 23792260

2013

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE Older age, male sex, African-American race, elevated CEA and not undergoing curative surgery were independent risk factors of cardiovascular mortality in patients with colorectal cancer. 30604158

2019

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE A microfluidic paper analytical device (μPAD) was created for the sensitive quantification of cancer antigens, carcinoembryonic antigen (CEA) and carbohydrate antigen 19-9 (CA 19-9), from human whole blood and serum, toward diagnosis and prognosis of colorectal cancer. 28922620

2018

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 GeneticVariation BEFREE Although many studies on CEA promoter and ST13 gene were reported but no construct has been performed to combine both of them as a new strategy for colorectal cancer (CRC) specific therapy. 23077639

2012

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE Generation of carcinoembryonic antigen (CEA)-specific T-cell responses in HLA-A*0201 and HLA-A*2402 late-stage colorectal cancer patients after vaccination with dendritic cells loaded with CEA peptides. 15102666

2004

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 AlteredExpression BEFREE We conclude that the induction of the CEA-gene expression by sodium butyrate in colorectal-cancer cells is mediated by both transcriptional and post-transcriptional mechanisms, with CEA mRNA stability as one of the major check-points. 2268282

1990

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 AlteredExpression BEFREE Quantitative estimation of CEA and CK20 expression in tumour tissue of colorectal cancer and its liver metastases with reverse transcription and real-time PCR. 16739357

2006

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE Overall, CEA remains a reliable predictor of recurrence and survival after curative surgery in patients with colorectal cancer. 30822523

2019

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE The CEAwatch randomized trial showed that follow-up with intensive carcinoembryonic antigen (CEA) monitoring (CEAwatch protocol) was better than care as usual (CAU) for early postoperative detection of colorectal cancer recurrence. 28376235

2017

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE Glycan analysis of colorectal cancer samples reveals stage-dependent changes in CEA glycosylation patterns. 29507546

2018

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE Because multiple tumor antigens, including carcinoembryonic antigen (CEA) and survivin (SVV), have been frequently observed in human colorectal cancer, we investigated whether the expression of both CEA and SVV by co-transduction of adenovirus vectors into dendritic cells (DCs) could improve anti-tumor immunity in a murine colorectal cancer model. 20211203

2010

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 AlteredExpression BEFREE Overexpression of CEA is closely associated with liver metastasis, which is the main cause of death from colorectal cancer. 28588612

2017

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE Evaluation of Serum CEA, CA19-9, CA72-4, CA125 and Ferritin as Diagnostic Markers and Factors of Clinical Parameters for Colorectal Cancer. 29426902

2018

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 AlteredExpression BEFREE In conclusion, our study demonstrated that the detection of CEA mRNA in peritoneal washings by TRC is a useful, rapid genetic diagnosis for the prediction of peritoneal recurrence and survival in patients with colorectal cancer. 17786336

2007

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
Malignant neoplasm of colon and/or rectum
0.100 Biomarker BEFREE In conclusion, our results revealed that FBW7 suppressed migration through regulation of the HIF1α/CEACAM5 axis in colorectal cancer. 29910683

2018