Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.400 Biomarker CTD_human

Entrez Id: 4087
Gene Symbol: SMAD2
SMAD2
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.400 GeneticVariation UNIPROT

Entrez Id: 207
Gene Symbol: AKT1
AKT1
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.400 Biomarker CTD_human

Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.400 Biomarker CTD_human

Entrez Id: 6714
Gene Symbol: SRC
SRC
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.390 Biomarker CTD_human

Entrez Id: 8313
Gene Symbol: AXIN2
AXIN2
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.360 Biomarker CTD_human

Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.350 Biomarker CTD_human

Entrez Id: 79695
Gene Symbol: GALNT12
GALNT12
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.320 Biomarker CTD_human

Entrez Id: 2033
Gene Symbol: EP300
EP300
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.320 Biomarker CTD_human

Entrez Id: 201163
Gene Symbol: FLCN
FLCN
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.310 Biomarker CTD_human

Entrez Id: 10395
Gene Symbol: DLC1
DLC1
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.310 Biomarker CTD_human

Entrez Id: 701
Gene Symbol: BUB1B
BUB1B
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.300 Biomarker CTD_human

Entrez Id: 1048
Gene Symbol: CEACAM5
CEACAM5
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.100 AlteredExpression BEFREE Differences in messenger RNA expression of carcinoembryonic antigen in surgical specimens of colorectal carcinoma. 1290028

1993

Entrez Id: 1630
Gene Symbol: DCC
DCC
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.600 AlteredExpression BEFREE Loss of expression of the DCC gene during progression of colorectal carcinomas in familial adenomatous polyposis and non-familial adenomatous polyposis patients. 1319833

1992

Entrez Id: 4313
Gene Symbol: MMP2
MMP2
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.400 Biomarker BEFREE We undertook an in situ hybridization study to localize the mRNAs for the 72 kda type IV collagenase (MMP-2) and its specific inhibitor (TIMP-2) in 12 colorectal carcinomas, 3 adenomas, and 4 uninvolved resection margins to see how their distributions correlated with that of the reported distribution of MMP-2 protein. 1323219

1992

Entrez Id: 7077
Gene Symbol: TIMP2
TIMP2
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.040 Biomarker BEFREE We undertook an in situ hybridization study to localize the mRNAs for the 72 kda type IV collagenase (MMP-2) and its specific inhibitor (TIMP-2) in 12 colorectal carcinomas, 3 adenomas, and 4 uninvolved resection margins to see how their distributions correlated with that of the reported distribution of MMP-2 protein. 1323219

1992

Entrez Id: 5906
Gene Symbol: RAP1A
RAP1A
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.010 GeneticVariation BEFREE This suggests that loss of heterozygosity is not a common mechanism of inactivation at the Krev-1 locus in colorectal cancer. 1345809

1992

Entrez Id: 6175
Gene Symbol: RPLP0
RPLP0
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.020 AlteredExpression BEFREE These findings support a common increased expression of selected gene products in different tumors of endodermal origin and suggest that increased P0 expression, in line with certain other ribosomal proteins, may be associated with human colorectal cancer progression and biological aggressiveness. 1350508

1992

Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.090 AlteredExpression BEFREE Using Northern and dot-blot analysis we examined normal and tumor tissue from 29 patients with colorectal carcinomas for the expression and amplification of c-myc, c-fos and c-Ha-ras proto-oncogenes. 1373678

1992

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.400 AlteredExpression BEFREE Expression of p53 protein in invasive colorectal carcinomas of different histologic types. 1451054

1993

Entrez Id: 5423
Gene Symbol: POLB
POLB
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.020 GeneticVariation BEFREE DNA polymerase beta mutations in human colorectal cancer. 1511447

1992

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.400 Biomarker BEFREE Allelic loss was studied for chromosomes 5, 17, and 18, and immunohistochemical analysis was done of the p53 protein product in tumors from 91 patients with colorectal cancer. 1516028

1992

Entrez Id: 3105
Gene Symbol: HLA-A
HLA-A
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.100 AlteredExpression BEFREE In the course of investigating the regulation of HLA-A and HLA-B mRNA in human colorectal carcinoma cell lines, we have noticed a noncoordinate expression of the HLA mRNA in some of these cell lines. 1517566

1992

Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.050 AlteredExpression BEFREE In the course of investigating the regulation of HLA-A and HLA-B mRNA in human colorectal carcinoma cell lines, we have noticed a noncoordinate expression of the HLA mRNA in some of these cell lines. 1517566

1992

Entrez Id: 324
Gene Symbol: APC
APC
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.600 GeneticVariation BEFREE Here we report that sequence analysis of 41 colorectal tumours revealed that the majority of colorectal carcinomas (60%) and adenomas (63%) contained a mutated APC gene. 1528264

1992