Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 13
Gene Symbol: AADAC
AADAC
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.010 AlteredExpression BEFREE Transfection of precursor miR-34b or miR-34c into CRC cells induced dramatic changes in the gene expression profile, and there was significant overlap between the genes down-regulated by miR-34b/c and those down-regulated by DAC. 18519671

2008

Entrez Id: 15
Gene Symbol: AANAT
AANAT
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.020 Biomarker BEFREE AA-NAT, MT1 and MT2 Correlates with Cancer Stem-Like Cell Markers in Colorectal Cancer: Study of the Influence of Stage and p53 Status of Tumors. 28604612

2018

Entrez Id: 15
Gene Symbol: AANAT
AANAT
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.020 AlteredExpression BEFREE Finally, a significant correlation was observed between AA-NAT and edn-1 expression downregulation in human colorectal cancer tissues. 24628039

2014

Entrez Id: 19
Gene Symbol: ABCA1
ABCA1
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.300 Biomarker CTD_human The role of ABC transporters in progression and clinical outcome of colorectal cancer. 22294766

2012

Entrez Id: 10349
Gene Symbol: ABCA10
ABCA10
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.300 Biomarker CTD_human The role of ABC transporters in progression and clinical outcome of colorectal cancer. 22294766

2012

Entrez Id: 26154
Gene Symbol: ABCA12
ABCA12
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.300 Biomarker CTD_human The role of ABC transporters in progression and clinical outcome of colorectal cancer. 22294766

2012

Entrez Id: 154664
Gene Symbol: ABCA13
ABCA13
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.300 Biomarker CTD_human The role of ABC transporters in progression and clinical outcome of colorectal cancer. 22294766

2012

Entrez Id: 21
Gene Symbol: ABCA3
ABCA3
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.300 Biomarker CTD_human The role of ABC transporters in progression and clinical outcome of colorectal cancer. 22294766

2012

Entrez Id: 24
Gene Symbol: ABCA4
ABCA4
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.300 Biomarker CTD_human The role of ABC transporters in progression and clinical outcome of colorectal cancer. 22294766

2012

Entrez Id: 23461
Gene Symbol: ABCA5
ABCA5
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.300 Biomarker CTD_human The role of ABC transporters in progression and clinical outcome of colorectal cancer. 22294766

2012

Entrez Id: 23460
Gene Symbol: ABCA6
ABCA6
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.300 Biomarker CTD_human The role of ABC transporters in progression and clinical outcome of colorectal cancer. 22294766

2012

Entrez Id: 10351
Gene Symbol: ABCA8
ABCA8
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.300 Biomarker CTD_human The role of ABC transporters in progression and clinical outcome of colorectal cancer. 22294766

2012

Entrez Id: 10350
Gene Symbol: ABCA9
ABCA9
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.300 Biomarker CTD_human The role of ABC transporters in progression and clinical outcome of colorectal cancer. 22294766

2012

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.400 Biomarker BEFREE Chemosensitivity patterns and expression of human multidrug resistance-associated MDR1 gene by human gastric and colorectal carcinoma cell lines. 1967320

1990

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.400 Biomarker BEFREE Bufalin reverses ABCB1-mediated drug resistance in colorectal cancer. 28624793

2018

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.400 Biomarker BEFREE Variants in CDA and ABCB1 are predictors of capecitabine-related adverse reactions in colorectal cancer. 25691056

2016

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.400 GeneticVariation BEFREE Association between MDR1 C3435T polymorphism and colorectal cancer risk: A meta-analysis. 29390571

2018

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.400 GeneticVariation BEFREE Effects of genetic polymorphisms of MDR1, FMO3 and CYP1A2 on susceptibility to colorectal cancer in Koreans. 16800822

2006

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.400 AlteredExpression BEFREE Expression of the mdr1 gene in human colorectal carcinomas: relationship with multidrug resistance inferred from analysis of human colorectal carcinoma cell lines. 1537074

1992

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.400 AlteredExpression BEFREE In the present study, we showed that PIK3CA and PIK3CB are upregulated in CRCs and positively correlated with MDR-1, LRP, and GST-π. 26747178

2017

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.400 GeneticVariation BEFREE Association between the C3435T polymorphism of ABCB1/MDR1 gene (rs1045642) and colorectal cancer susceptibility : a meta-analysis based on 11,339 subjects. 23504525

2013

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.400 Biomarker CTD_human The role of ABC transporters in progression and clinical outcome of colorectal cancer. 22294766

2012

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.400 AlteredExpression BEFREE The resulting cell line (AMC5/B1) was 5.3-fold resistant to berberrubine in the absence of MDR1 overexpression. 11901227

2002

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.400 Biomarker BEFREE Resveratrol induces AMPK-dependent MDR1 inhibition in colorectal cancer HCT116/L-OHP cells by preventing activation of NF-κB signaling and suppressing cAMP-responsive element transcriptional activity. 26124005

2016

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.400 Biomarker CTD_human This study suggests that low ABCB1 mRNA levels are an early event in CRC development and that the two polymorphisms affect ABCB1 mRNA levels whereas low NFKB1 mRNA levels occur later in carcinogenesis. 23977225

2014