×
Entrez Id: 1050
Gene Symbol: CEBPA
CEBPA
Leukemia, Myelocytic, Acute
1.000
CausalMutation
CLINVAR
×
Entrez Id: 1050
Gene Symbol: CEBPA
CEBPA
Leukemia, Myelocytic, Acute
1.000
GeneticVariation
CLINVAR
×
Entrez Id: 1441
Gene Symbol: CSF3R
CSF3R
Leukemia, Myelocytic, Acute
0.500
GeneticVariation
CLINVAR
Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia.
23634996 2013
×
Entrez Id: 51428
Gene Symbol: DDX41
DDX41
Leukemia, Myelocytic, Acute
0.190
CausalMutation
CLINVAR
×
Entrez Id: 134218
Gene Symbol: DNAJC21
DNAJC21
Leukemia, Myelocytic, Acute
0.100
CausalMutation
CLINVAR
×
Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A
Leukemia, Myelocytic, Acute
0.800
CausalMutation
CLINVAR
DNMT3A mutations in acute myeloid leukemia.
21067377 2010
×
Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A
Leukemia, Myelocytic, Acute
0.800
CausalMutation
CLINVAR
[Analysis of DNMT3a gene mutations in acute myelogenous leukemia].
21518476 2011
×
Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A
Leukemia, Myelocytic, Acute
0.800
CausalMutation
CLINVAR
Impact of genetic features on treatment decisions in AML.
22160010 2011
×
Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A
Leukemia, Myelocytic, Acute
0.800
CausalMutation
CLINVAR
Screening for mutation R882 in the DNMT3A gene in Chinese patients with hematological disease.
22744846 2012
×
Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A
Leukemia, Myelocytic, Acute
0.800
GeneticVariation
CLINVAR
×
Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A
Leukemia, Myelocytic, Acute
0.800
CausalMutation
CLINVAR
The R882H DNMT3A mutation associated with AML dominantly inhibits wild-type DNMT3A by blocking its ability to form active tetramers.
24656771 2014
×
Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A
Leukemia, Myelocytic, Acute
0.800
CausalMutation
CLINVAR
The role of mutations in epigenetic regulators in myeloid malignancies.
22898539 2012
×
Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A
Leukemia, Myelocytic, Acute
0.800
CausalMutation
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011 2016
×
Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A
Leukemia, Myelocytic, Acute
0.800
CausalMutation
CLINVAR
Cancer stem cells: Tracing clones.
22898540 2012
×
Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A
Leukemia, Myelocytic, Acute
0.800
CausalMutation
CLINVAR
Retroviral oncogenes: a historical primer.
22898541 2012
×
Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A
Leukemia, Myelocytic, Acute
0.800
CausalMutation
CLINVAR
Molecular evaluation of DNMT3A and IDH1/2 gene mutation: frequency, distribution pattern and associations with additional molecular markers in normal karyotype Indian acute myeloid leukemia patients.
24606448 2014
×
Entrez Id: 2120
Gene Symbol: ETV6
ETV6
Leukemia, Myelocytic, Acute
0.800
CausalMutation
CLINVAR
×
Entrez Id: 2322
Gene Symbol: FLT3
FLT3
Leukemia, Myelocytic, Acute
1.000
CausalMutation
CLINVAR
Mutations in the tyrosine kinase domain of FLT3 define a new molecular mechanism of acquired drug resistance to PTK inhibitors in FLT3-ITD-transformed hematopoietic cells.
14604974 2004
×
Entrez Id: 2322
Gene Symbol: FLT3
FLT3
Leukemia, Myelocytic, Acute
1.000
GeneticVariation
CLINVAR
Exome sequencing identifies recurring FLT3 N676K mutations in core-binding factor leukemia.
23878140 2013
×
Entrez Id: 2322
Gene Symbol: FLT3
FLT3
Leukemia, Myelocytic, Acute
1.000
CausalMutation
CLINVAR
Prospective enterprise-level molecular genotyping of a cohort of cancer patients.
25157968 2014
×
Entrez Id: 2322
Gene Symbol: FLT3
FLT3
Leukemia, Myelocytic, Acute
1.000
CausalMutation
CLINVAR
Prolonged exposure to FLT3 inhibitors leads to resistance via activation of parallel signaling pathways.
17047150 2007
×
Entrez Id: 2322
Gene Symbol: FLT3
FLT3
Leukemia, Myelocytic, Acute
1.000
CausalMutation
CLINVAR
Crowding induces live cell extrusion to maintain homeostatic cell numbers in epithelia.
22504183 2012
×
Entrez Id: 2322
Gene Symbol: FLT3
FLT3
Leukemia, Myelocytic, Acute
1.000
GeneticVariation
CLINVAR
Roles of tyrosine residues 845, 892 and 922 in constitutive activation of murine FLT3 kinase domain mutant.
16091740 2005
×
Entrez Id: 2322
Gene Symbol: FLT3
FLT3
Leukemia, Myelocytic, Acute
1.000
CausalMutation
CLINVAR
Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies.
11290608 2001
×
Entrez Id: 2322
Gene Symbol: FLT3
FLT3
Leukemia, Myelocytic, Acute
1.000
CausalMutation
CLINVAR
Sorafenib treatment of FLT3-ITD(+) acute myeloid leukemia: favorable initial outcome and mechanisms of subsequent nonresponsiveness associated with the emergence of a D835 mutation.
22368270 2012