×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Human homolog of the MutY repair protein (hMYH) physically interacts with proteins involved in long patch DNA base excision repair.
11092888 2001
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
Human homolog of the MutY repair protein (hMYH) physically interacts with proteins involved in long patch DNA base excision repair.
11092888 2001
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Biallelic germline mutations in MYH predispose to multiple colorectal adenoma and somatic G:C-->T:A mutations.
12393807 2002
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
Functional interaction of MutY homolog with proliferating cell nuclear antigen in fission yeast, Schizosaccharomyces pombe.
11805113 2002
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
Human MutY homolog, a DNA glycosylase involved in base excision repair, physically and functionally interacts with mismatch repair proteins human MutS homolog 2/human MutS homolog 6.
11801590 2002
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
Multiple colorectal adenomas, classic adenomatous polyposis, and germ-line mutations in MYH.
12606733 2003
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Germline mutations but not somatic changes at the MYH locus contribute to the pathogenesis of unselected colorectal cancers.
12707038 2003
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Autosomal recessive colorectal adenomatous polyposis due to inherited mutations of MYH.
12853198 2003
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Carcinogenesis in MYH-associated polyposis follows a distinct genetic pathway.
14633673 2003
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Multiple colorectal adenomas, classic adenomatous polyposis, and germ-line mutations in MYH.
12606733 2003
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
Carcinogenesis in MYH-associated polyposis follows a distinct genetic pathway.
14633673 2003
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
High frequency of MYH gene mutations in a subset of patients with familial adenomatous polyposis.
15188161 2004
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
Comprehensive analysis of the contribution of germline MYH variation to early-onset colorectal cancer.
14991577 2004
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
Germline MUTYH (MYH) mutations in Portuguese individuals with multiple colorectal adenomas.
15366000 2004
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Germline MUTYH (MYH) mutations in Portuguese individuals with multiple colorectal adenomas.
15366000 2004
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
MYH mutations in patients with attenuated and classic polyposis and with young-onset colorectal cancer without polyps.
15236166 2004
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Colorectal cancer and inherited mutations in base-excision repair.
15465463 2004
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
Mutations of APC and MYH in unrelated Italian patients with adenomatous polyposis coli.
16134147 2005
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Attenuated familial adenomatous polyposis and Muir-Torre syndrome linked to compound biallelic constitutional MYH gene mutations.
16207212 2005
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Germline mutations of the MYH gene in Japanese patients with multiple colorectal adenomas.
15890374 2005
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Mutations of APC and MYH in unrelated Italian patients with adenomatous polyposis coli.
16134147 2005
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Mutation analysis of the MYH gene in an Australian series of colorectal polyposis patients with or without germline APC mutations.
15761860 2005
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
The potential for increased clinical sensitivity in genetic testing for polyposis colorectal cancer through the analysis of MYH mutations in North American patients.
15635083 2005
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
Functional characterization of two human MutY homolog (hMYH) missense mutations (R227W and V232F) that lie within the putative hMSH6 binding domain and are associated with hMYH polyposis.
15673720 2005
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Germline susceptibility to colorectal cancer due to base-excision repair gene defects.
15931596 2005