×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
A germline homozygous mutation in the base-excision repair gene NTHL1 causes adenomatous polyposis and colorectal cancer.
25938944 2015
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
A large-scale meta-analysis to refine colorectal cancer risk estimates associated with MUTYH variants.
21063410 2010
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
A structural hinge in eukaryotic MutY homologues mediates catalytic activity and Rad9-Rad1-Hus1 checkpoint complex interactions.
20816984 2010
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
Adenine DNA glycosylase activity of 14 human MutY homolog (MUTYH) variant proteins found in patients with colorectal polyposis and cancer.
20848659 2010
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Adenine DNA glycosylase activity of 14 human MutY homolog (MUTYH) variant proteins found in patients with colorectal polyposis and cancer.
20848659 2010
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Adenine removal activity and bacterial complementation with the human MutY homologue (MUTYH) and Y165C, G382D, P391L and Q324R variants associated with colorectal cancer.
19836313 2009
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Alterations of the base excision repair gene MUTYH in sporadic colorectal cancer.
22641385 2012
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Analysis of inherited MYH/(MutYH) mutations in British Asian patients with colorectal cancer.
17369389 2007
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Analysis of MUTYH genotypes and colorectal phenotypes in patients With MUTYH-associated polyposis.
19032956 2009
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
Analysis of MUTYH genotypes and colorectal phenotypes in patients With MUTYH-associated polyposis.
19032956 2009
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
APC or MUTYH mutations account for the majority of clinically well-characterized families with FAP and AFAP phenotype and patients with more than 30 adenomas.
19793053 2009
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
APC or MUTYH mutations account for the majority of clinically well-characterized families with FAP and AFAP phenotype and patients with more than 30 adenomas.
19793053 2009
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Association of monoallelic MUTYH mutation among Egyptian patients with colorectal cancer.
27631816 2017
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
Atomic substitution reveals the structural basis for substrate adenine recognition and removal by adenine DNA glycosylase.
19841264 2009
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Attenuated familial adenomatous polyposis and Muir-Torre syndrome linked to compound biallelic constitutional MYH gene mutations.
16207212 2005
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Autosomal recessive colorectal adenomatous polyposis due to inherited mutations of MYH.
12853198 2003
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
Base excision repair and the role of MUTYH.
19725997 2007
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Base-excision repair of oxidative DNA damage.
17581577 2007
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Biallelic germline mutations in MYH predispose to multiple colorectal adenoma and somatic G:C-->T:A mutations.
12393807 2002
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Cancer risks for monoallelic MUTYH mutation carriers with a family history of colorectal cancer.
21171015 2011
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Cancer-associated variants and a common polymorphism of MUTYH exhibit reduced repair of oxidative DNA damage using a GFP-based assay in mammalian cells.
22926731 2012
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
Candidate colorectal cancer predisposing gene variants in Chinese early-onset and familial cases.
25892863 2015
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Candidate colorectal cancer predisposing gene variants in Chinese early-onset and familial cases.
25892863 2015
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
CausalMutation
CLINVAR
Carcinogenesis in MYH-associated polyposis follows a distinct genetic pathway.
14633673 2003
×
Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
Neoplastic Syndromes, Hereditary
0.100
GeneticVariation
CLINVAR
Carcinogenesis in MYH-associated polyposis follows a distinct genetic pathway.
14633673 2003