Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C3887645
Disease: Job Syndrome
Job Syndrome
0.800 Biomarker GENOMICS_ENGLAND

Entrez Id: 6774
Gene Symbol: STAT3
STAT3
AUTOIMMUNE DISEASE, MULTISYSTEM, INFANTILE-ONSET, 1
0.700 Biomarker CTD_human

Entrez Id: 6774
Gene Symbol: STAT3
STAT3
T-Cell Large Granular Lymphocyte Leukemia
0.600 CausalMutation CGI

Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0010346
Disease: Crohn Disease
Crohn Disease
0.500 Biomarker GENOMICS_ENGLAND

Entrez Id: 6774
Gene Symbol: STAT3
STAT3
Hyper-Ige Recurrent Infection Syndrome, Autosomal Dominant
0.500 Biomarker CTD_human

Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0023418
Disease: leukemia
leukemia
0.400 Biomarker GENOMICS_ENGLAND

Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0024115
Disease: Lung diseases
Lung diseases
0.330 Biomarker GENOMICS_ENGLAND

Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0878544
Disease: Cardiomyopathies
Cardiomyopathies
0.340 Biomarker CTD_human These results provide direct evidence that STAT3 transduces not only a hypertrophic signal but also a protective signal against Dox-induced cardiomyopathy by inhibiting reduction of cardiac contractile genes and inducing cardiac protective factors. 10618415

2000

Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0878544
Disease: Cardiomyopathies
Cardiomyopathies
0.340 Therapeutic CTD_human These results provide direct evidence that STAT3 transduces not only a hypertrophic signal but also a protective signal against Dox-induced cardiomyopathy by inhibiting reduction of cardiac contractile genes and inducing cardiac protective factors. 10618415

2000

Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly
0.300 Biomarker CTD_human Signal transducer and activator of transcription 3 in the heart transduces not only a hypertrophic signal but a protective signal against doxorubicin-induced cardiomyopathy. 10618415

2000

Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0033141
Disease: Cardiomyopathies, Primary
Cardiomyopathies, Primary
0.300 Therapeutic CTD_human Signal transducer and activator of transcription 3 in the heart transduces not only a hypertrophic signal but a protective signal against doxorubicin-induced cardiomyopathy. 10618415

2000

Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0033141
Disease: Cardiomyopathies, Primary
Cardiomyopathies, Primary
0.300 Biomarker CTD_human Signal transducer and activator of transcription 3 in the heart transduces not only a hypertrophic signal but a protective signal against doxorubicin-induced cardiomyopathy. 10618415

2000

Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0036529
Disease: Myocardial Diseases, Secondary
Myocardial Diseases, Secondary
0.300 Therapeutic CTD_human Signal transducer and activator of transcription 3 in the heart transduces not only a hypertrophic signal but a protective signal against doxorubicin-induced cardiomyopathy. 10618415

2000

Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0036529
Disease: Myocardial Diseases, Secondary
Myocardial Diseases, Secondary
0.300 Biomarker CTD_human Signal transducer and activator of transcription 3 in the heart transduces not only a hypertrophic signal but a protective signal against doxorubicin-induced cardiomyopathy. 10618415

2000

Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C1383860
Disease: Cardiac Hypertrophy
Cardiac Hypertrophy
0.300 Biomarker CTD_human Signal transducer and activator of transcription 3 in the heart transduces not only a hypertrophic signal but a protective signal against doxorubicin-induced cardiomyopathy. 10618415

2000

Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.400 Biomarker CTD_human STAT-3 is active during the regenerative growth of the liver, but there are hardly any data about its presence in liver tumours. 12957465

2003

Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0345904
Disease: Malignant neoplasm of liver
Malignant neoplasm of liver
0.400 Biomarker CTD_human STAT-3 activity in chemically-induced hepatocellular carcinoma. 12957465

2003

Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast
0.400 Biomarker CTD_human Cross-talk between endocrine-disrupting chemicals and cytokine signaling through estrogen receptors. 14975756

2004

Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.400 Biomarker CTD_human Cross-talk between endocrine-disrupting chemicals and cytokine signaling through estrogen receptors. 14975756

2004

Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate
0.400 Biomarker CTD_human Cross-talk between endocrine-disrupting chemicals and cytokine signaling through estrogen receptors. 14975756

2004

Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.400 Biomarker CTD_human Cross-talk between endocrine-disrupting chemicals and cytokine signaling through estrogen receptors. 14975756

2004

Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.400 Biomarker CTD_human Cross-talk between endocrine-disrupting chemicals and cytokine signaling through estrogen receptors. 14975756

2004

Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human
0.300 Biomarker CTD_human Cross-talk between endocrine-disrupting chemicals and cytokine signaling through estrogen receptors. 14975756

2004

Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C4704874
Disease: Mammary Carcinoma, Human
Mammary Carcinoma, Human
0.300 Biomarker CTD_human Cross-talk between endocrine-disrupting chemicals and cytokine signaling through estrogen receptors. 14975756

2004

Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0003865
Disease: Arthritis, Adjuvant-Induced
Arthritis, Adjuvant-Induced
0.300 Biomarker CTD_human Local activation of STAT-1 and STAT-3 in the inflamed synovium during zymosan-induced arthritis: exacerbation of joint inflammation in STAT-1 gene-knockout mice. 15188379

2004