Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2896
Gene Symbol: GRN
GRN
CUI: C0263009
Disease: Sclerosis of the skin
Sclerosis of the skin 		0.020 Biomarker BEFREE Progranulin may also be involved in the inflammatory process associated with progressive skin sclerosis in early dcSSc. 26245842

2015
Entrez Id: 2896
Gene Symbol: GRN
GRN
CUI: C0263009
Disease: Sclerosis of the skin
Sclerosis of the skin 		0.020 Biomarker BEFREE The reduced progression of skin sclerosis in PGRN-deficient mice was associated with down-regulation of transforming growth factor (TGF)-β receptor I (TβR I) and decreased level of phosphorylated Smad3, with correspondingly impaired expression of its downstream target gene connective tissue growth factor (CTGF) in skin lesion. 31108104

2019