×
Entrez Id:
53347
Gene Symbol:
UBASH3A
UBASH3A
Cholangitis, Sclerosing
0.400
Biomarker
CTD_human
Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease.
27992413
2017
×
Entrez Id:
53347
Gene Symbol:
UBASH3A
UBASH3A
Cholangitis, Sclerosing
0.400
GeneticVariation
GWASCAT
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.
26974007
2016
×
Entrez Id:
4485
Gene Symbol:
MST1
MST1
Cholangitis, Sclerosing
0.400
GeneticVariation
GWASCAT
Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease.
27992413
2017
×
Entrez Id:
4843
Gene Symbol:
NOS2
NOS2
Cholangitis, Sclerosing
0.400
Biomarker
CTD_human
Cytokine-stimulated nitric oxide production inhibits adenylyl cyclase and cAMP-dependent secretion in cholangiocytes.
12612912
2003
×
Entrez Id:
4843
Gene Symbol:
NOS2
NOS2
Cholangitis, Sclerosing
0.400
GeneticVariation
GWASCAT
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.
26974007
2016
×
Entrez Id:
53347
Gene Symbol:
UBASH3A
UBASH3A
Cholangitis, Sclerosing
0.400
GeneticVariation
GWASCAT
Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease.
27992413
2017
×
Entrez Id:
4485
Gene Symbol:
MST1
MST1
Cholangitis, Sclerosing
0.400
GeneticVariation
GWASCAT
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.
26974007
2016
×
Entrez Id:
4485
Gene Symbol:
MST1
MST1
Cholangitis, Sclerosing
0.400
GeneticVariation
GWASCAT
Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis.
23603763
2013
×
Entrez Id:
4485
Gene Symbol:
MST1
MST1
Cholangitis, Sclerosing
0.400
Biomarker
CTD_human
Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci.
21151127
2011
×
Entrez Id:
4485
Gene Symbol:
MST1
MST1
Cholangitis, Sclerosing
0.400
GeneticVariation
GWASCAT
Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci.
21151127
2011
×
Entrez Id:
5244
Gene Symbol:
ABCB4
ABCB4
Cholangitis, Sclerosing
0.320
Biomarker
CTD_human
Galunisertib modifies the liver fibrotic composition in the Abcb4Ko mouse model.
29808285
2018
×
Entrez Id:
5244
Gene Symbol:
ABCB4
ABCB4
Cholangitis, Sclerosing
0.320
Biomarker
BEFREE
Because MDR2 (rodent orthologue of human MDR3 ) knockout mice develop sclerosing cholangitis , it is attractive to speculate that MDR3 defects could also play an important role in cholangiopathies in humans.
17295178
2007
×
Entrez Id:
5244
Gene Symbol:
ABCB4
ABCB4
Cholangitis, Sclerosing
0.320
GeneticVariation
BEFREE
To generalize these observations, we suppressed β-catenin in Mdr2 knockout (KO) mice, which develop sclerosing cholangitis due to regurgitation of BA from leaky ducts.
31489648
2019
×
Entrez Id:
5244
Gene Symbol:
ABCB4
ABCB4
Cholangitis, Sclerosing
0.320
Biomarker
CTD_human
Multidrug resistance gene 2 knockout mice (Mdr2 (-/-)) represent a well-characterized model for sclerosing cholangitis .
16472600
2006
×
Entrez Id:
3091
Gene Symbol:
HIF1A
HIF1A
Cholangitis, Sclerosing
0.300
Biomarker
CTD_human
Consistent with a role for HIFs in liver fibrosis in cholestatic liver disease, nuclear HIF-1 α protein was present in macrophages, hepatocytes, and fibroblasts in the livers from patients with primary biliary cirrhosis and primary sclerosing cholangitis .
22271822
2012
×
Entrez Id:
10018
Gene Symbol:
BCL2L11
BCL2L11
Cholangitis, Sclerosing
0.300
Biomarker
CTD_human
Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci.
21151127
2011
×
Entrez Id:
8209
Gene Symbol:
GATD3A
GATD3A
Cholangitis, Sclerosing
0.110
GeneticVariation
GWASCAT
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.
26974007
2016
×
Entrez Id:
8209
Gene Symbol:
GATD3A
GATD3A
Cholangitis, Sclerosing
0.110
Biomarker
BEFREE
PDX-1/Hes-1 interactions determine cholangiocyte proliferative response to injury in rodents: possible implications for sclerosing cholangitis .
23207146
2013
×
Entrez Id:
6311
Gene Symbol:
ATXN2
ATXN2
Cholangitis, Sclerosing
0.100
GeneticVariation
GWASCAT
Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease.
27992413
2017
×
Entrez Id:
57178
Gene Symbol:
ZMIZ1
ZMIZ1
Cholangitis, Sclerosing
0.100
GeneticVariation
GWASCAT
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.
26974007
2016
LINC00824
Cholangitis, Sclerosing
0.100
GeneticVariation
GWASCAT
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.
26974007
2016
×
Entrez Id:
10666
Gene Symbol:
CD226
CD226
Cholangitis, Sclerosing
0.100
GeneticVariation
GWASCAT
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.
26974007
2016
LINC02213
Cholangitis, Sclerosing
0.100
GeneticVariation
GWASCAT
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.
26974007
2016
×
Entrez Id:
116028
Gene Symbol:
RMI2
RMI2
Cholangitis, Sclerosing
0.100
GeneticVariation
GWASCAT
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.
26974007
2016
FAM177A1
Cholangitis, Sclerosing
0.100
GeneticVariation
GWASCAT
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.
26974007
2016