×
Entrez Id: 1392
Gene Symbol: CRH
CRH
Cocaine Abuse
0.300
Biomarker
CTD_human
Brain corticotropin-releasing factor mediates 'anxiety-like' behavior induced by cocaine withdrawal in rats.
7796157 1995
×
Entrez Id: 3351
Gene Symbol: HTR1B
HTR1B
Cocaine Abuse
0.500
Biomarker
CTD_human
Increased vulnerability to cocaine in mice lacking the serotonin-1B receptor.
9603521 1998
×
Entrez Id: 3351
Gene Symbol: HTR1B
HTR1B
Cocaine Abuse
0.500
Therapeutic
CTD_human
Increased vulnerability to cocaine in mice lacking the serotonin-1B receptor.
9603521 1998
×
Entrez Id: 887
Gene Symbol: CCKBR
CCKBR
Cocaine Abuse
0.300
Biomarker
CTD_human
Thus, a potential therapeutic role for CCK-A antagonists in the treatment of ethanol abuse and for CCK-B antagonists in the treatment of cocaine abuse is proposed.
9922984 1998
×
Entrez Id: 9607
Gene Symbol: CARTPT
CARTPT
Cocaine Abuse
0.510
Biomarker
PSYGENET
The role of dopamine, dynorphin, and CART systems in the ventral striatum and amygdala in cocaine abuse .
10415667 1999
×
Entrez Id: 1392
Gene Symbol: CRH
CRH
Cocaine Abuse
0.300
Biomarker
CTD_human
A role for the bed nucleus of the stria terminalis, but not the amygdala, in the effects of corticotropin-releasing factor on stress-induced reinstatement of cocaine seeking.
10516337 1999
×
Entrez Id: 1814
Gene Symbol: DRD3
DRD3
Cocaine Abuse
0.500
Biomarker
CTD_human
Homozygosity at the dopamine DRD3 receptor gene in cocaine dependence.
10523822 1999
×
Entrez Id: 1814
Gene Symbol: DRD3
DRD3
Cocaine Abuse
0.500
Therapeutic
CTD_human
Homozygosity at the dopamine DRD3 receptor gene in cocaine dependence.
10523822 1999
×
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
Cocaine Abuse
0.520
Biomarker
PSYGENET
The effects of chronic cocaine abuse on transcriptional regulation of human dopamine transporter (DAT ) mRNA in midbrain dopaminergic neurons was assessed by reverse transcription-polymerase chain reaction (RT-PCR).
10581411 1999
×
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
Cocaine Abuse
0.540
Biomarker
CTD_human
Dopamine D1- and D2-like receptor mechanisms in relapse to cocaine-seeking behavior: effects of selective antagonists and agonists.
10900248 2000
×
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
Cocaine Abuse
0.540
Therapeutic
CTD_human
Dopamine D1- and D2-like receptor mechanisms in relapse to cocaine-seeking behavior: effects of selective antagonists and agonists.
10900248 2000
×
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
Cocaine Abuse
0.300
Biomarker
CTD_human
Antagonism of 5-hydroxytryptamine(2a) receptors attenuates the behavioral effects of cocaine in rats.
11259563 2001
×
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
Cocaine Abuse
0.520
Therapeutic
CTD_human
Molecular mechanisms of cocaine reward: combined dopamine and serotonin transporter knockouts eliminate cocaine place preference.
11320258 2001
×
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
Cocaine Abuse
0.520
Biomarker
CTD_human
Molecular mechanisms of cocaine reward: combined dopamine and serotonin transporter knockouts eliminate cocaine place preference.
11320258 2001
×
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
Cocaine Abuse
0.310
Biomarker
CTD_human
Molecular mechanisms of cocaine reward: combined dopamine and serotonin transporter knockouts eliminate cocaine place preference.
11320258 2001
×
Entrez Id: 1385
Gene Symbol: CREB1
CREB1
Cocaine Abuse
0.300
Biomarker
CTD_human
Different requirements for cAMP response element binding protein in positive and negative reinforcing properties of drugs of abuse.
11717377 2001
×
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
Cocaine Abuse
0.520
Biomarker
CTD_human
Self-administration of cocaine and the cocaine analog RTI-113: relationship to dopamine transporter occupancy determined by PET neuroimaging in rhesus monkeys.
11746736 2002
×
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
Cocaine Abuse
0.520
Therapeutic
CTD_human
Self-administration of cocaine and the cocaine analog RTI-113: relationship to dopamine transporter occupancy determined by PET neuroimaging in rhesus monkeys.
11746736 2002
×
Entrez Id: 5443
Gene Symbol: POMC
POMC
Cocaine Abuse
0.300
Biomarker
CTD_human
Temporal concordance of cocaine effects on mood states and neuroendocrine hormones.
11750770 2002
×
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
Cocaine Abuse
0.540
Therapeutic
CTD_human
Relapse to cocaine- and heroin-seeking behavior mediated by dopamine D2 receptors is time-dependent and associated with behavioral sensitization.
11751029 2002
×
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
Cocaine Abuse
0.540
Biomarker
CTD_human
Relapse to cocaine- and heroin-seeking behavior mediated by dopamine D2 receptors is time-dependent and associated with behavioral sensitization.
11751029 2002
×
Entrez Id: 1392
Gene Symbol: CRH
CRH
Cocaine Abuse
0.300
Biomarker
CTD_human
A role for the CRF-containing pathway from central nucleus of the amygdala to bed nucleus of the stria terminalis in the stress-induced reinstatement of cocaine seeking in rats.
11797056 2001
×
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A
Cocaine Abuse
0.300
Biomarker
CTD_human
These findings point to a potential role for 5-HT1A antagonists in treatment of cocaine abuse .
11853856 2002
×
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
Cocaine Abuse
0.540
Therapeutic
CTD_human
Role of dopamine D2-like receptors in cocaine self-administration: studies with D2 receptor mutant mice and novel D2 receptor antagonists.
11923462 2002
×
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
Cocaine Abuse
0.540
Biomarker
CTD_human
Role of dopamine D2-like receptors in cocaine self-administration: studies with D2 receptor mutant mice and novel D2 receptor antagonists.
11923462 2002