Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer 		0.800 Biomarker GENOMICS_ENGLAND

Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer 		0.500 Biomarker CTD_human

Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer 		0.500 Biomarker GENOMICS_ENGLAND

Entrez Id: 4595
Gene Symbol: MUTYH
MUTYH
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer 		0.320 Biomarker CTD_human

Entrez Id: 324
Gene Symbol: APC
APC
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer 		0.320 Biomarker CTD_human

Entrez Id: 843
Gene Symbol: CASP10
CASP10
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer 		0.300 Biomarker CTD_human

Entrez Id: 3659
Gene Symbol: IRF1
IRF1
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer 		0.300 Biomarker CTD_human

Entrez Id: 1316
Gene Symbol: KLF6
KLF6
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer 		0.300 Biomarker CTD_human

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer 		0.800 Biomarker CLINGEN Expression of E- and P-cadherin in gastric carcinomas. 2009537

1991
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer 		0.800 Biomarker CLINGEN Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role. 2070412

1991
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer 		0.300 Therapeutic CTD_human Effects on tumour microcirculation in mice of misonidazole and tumour necrosis factor plus hyperthermia. 1733439

1992
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer 		0.300 Biomarker CTD_human Effects on tumour microcirculation in mice of misonidazole and tumour necrosis factor plus hyperthermia. 1733439

1992
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer 		0.800 Biomarker CLINGEN From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion. 8236461

1993
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer 		0.800 Biomarker CLINGEN A causal role for E-cadherin in the transition from adenoma to carcinoma. 9515965

1998
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer 		0.800 Biomarker CTD_human E-cadherin germline mutations in familial gastric cancer. 9537325

1998
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer 		0.800 Biomarker CLINGEN E-cadherin germline mutations in familial gastric cancer. 9537325

1998
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer 		0.800 GeneticVariation UNIPROT We screened five Korean familial gastric cancer patients to investigate germline mutations of the E-cadherin gene. 10319582

1999
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer 		0.800 Biomarker CTD_human We have confirmed that germline mutations in the CDH1 gene cause familial gastric cancer in non-Maori populations. 10072428

1999
Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer 		0.800 Biomarker CLINGEN We have confirmed that germline mutations in the CDH1 gene cause familial gastric cancer in non-Maori populations. 10072428

1999
Entrez Id: 4869
Gene Symbol: NPM1
NPM1
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer 		0.300 Biomarker CTD_human Decrease in nucleophosmin/B23 mRNA and telomerase activity during indomethacin-induced apoptosis of gastric KATO-III cancer cells. 10619186

1999
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer 		0.300 Biomarker CTD_human Overexpression of cyclooxygenase-2 protein is less frequent in gastric cancers with microsatellite instability. 10404093

1999
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer 		0.400 Biomarker CTD_human DNA adduct measurements, cell proliferation and tumor mutation induction in relation to tumor formation in B6C3F1 mice fed coal tar or benzo[a]pyrene. 10874023

2000
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer 		0.300 Biomarker CTD_human Overexpression of manganese superoxide dismutase mRNA may correlate with aggressiveness in gastric and colorectal adenocarcinomas. 10853026

2000
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer 		0.400 Biomarker CTD_human Point mutations of K-ras and H-ras genes in forestomach neoplasms from control B6C3F1 mice and following exposure to 1,3-butadiene, isoprene or chloroprene for up to 2-years. 11397402

2001
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C1708349
Disease: Hereditary Diffuse Gastric Cancer
Hereditary Diffuse Gastric Cancer 		0.300 Biomarker CTD_human Point mutations of K-ras and H-ras genes in forestomach neoplasms from control B6C3F1 mice and following exposure to 1,3-butadiene, isoprene or chloroprene for up to 2-years. 11397402

2001