Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3700
Gene Symbol: ITIH4
ITIH4
CUI: C0001175
Disease: Acquired Immunodeficiency Syndrome
Acquired Immunodeficiency Syndrome
0.100 Biomarker BEFREE AIDS is caused by a type 1 human immunodeficiency virus (HIV-1) and formation of a complex among the gp120, CD4 and CCR5/CXCR4 surface proteins represents a key-step in the infection. 15320730

2004

Entrez Id: 6441
Gene Symbol: SFTPD
SFTPD
CUI: C0001175
Disease: Acquired Immunodeficiency Syndrome
Acquired Immunodeficiency Syndrome
0.010 AlteredExpression LHGDN AIDS patients have increased surfactant protein D but normal mannose binding lectin levels in lung fluid. 17567900

2007

Entrez Id: 4153
Gene Symbol: MBL2
MBL2
CUI: C0001175
Disease: Acquired Immunodeficiency Syndrome
Acquired Immunodeficiency Syndrome
0.030 AlteredExpression LHGDN AIDS patients have increased surfactant protein D but normal mannose binding lectin levels in lung fluid. 17567900

2007

Entrez Id: 3558
Gene Symbol: IL2
IL2
CUI: C0001175
Disease: Acquired Immunodeficiency Syndrome
Acquired Immunodeficiency Syndrome
0.350 GeneticVariation BEFREE Acquired immune deficiency syndrome in childhood: impaired production of interleukin-2 by HIV (LAV/HTLV III) infected patients. 2954915

1987

Entrez Id: 51750
Gene Symbol: RTEL1
RTEL1
CUI: C0001175
Disease: Acquired Immunodeficiency Syndrome
Acquired Immunodeficiency Syndrome
0.010 Biomarker BEFREE AIDS-associated non-Hodgkin's lymphoma (AIDS-NHL) is almost invariably derived from B cells and is classified as high- or intermediate-grade NHL, according to the working formulation. 7993935

1994

Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C0001175
Disease: Acquired Immunodeficiency Syndrome
Acquired Immunodeficiency Syndrome
0.060 Biomarker BEFREE Interleukin-6 production in high-grade B lymphomas: correlation with the presence of malignant immunoblasts in acquired immunodeficiency syndrome and in human immunodeficiency virus-seronegative patients. 1320956

1992

Entrez Id: 3586
Gene Symbol: IL10
IL10
CUI: C0001175
Disease: Acquired Immunodeficiency Syndrome
Acquired Immunodeficiency Syndrome
0.080 Biomarker BEFREE IL-10 production in AIDS lymphomas was associated with the presence of Epstein-Barr virus (EBV) in lymphomatous cells (p = 0.02). 1330578

1992

Entrez Id: 3605
Gene Symbol: IL17A
IL17A
CUI: C0001175
Disease: Acquired Immunodeficiency Syndrome
Acquired Immunodeficiency Syndrome
0.010 Biomarker BEFREE IL-17A could have potential as a therapeutic cytokine for systemic C. albicans infections in immunocompromised patients with cancer or advanced acquired immunodeficiency syndrome. 15243941

2004

Entrez Id: 4486
Gene Symbol: MST1R
MST1R
CUI: C0001175
Disease: Acquired Immunodeficiency Syndrome
Acquired Immunodeficiency Syndrome
0.010 Biomarker BEFREE RON was detected in all control patients who were HIV seronegative (n = 7), whereas six of nine brain samples obtained from AIDS patients exhibited reduced RON protein. 15557181

2004

Entrez Id: 729230
Gene Symbol: CCR2
CCR2
CUI: C0001175
Disease: Acquired Immunodeficiency Syndrome
Acquired Immunodeficiency Syndrome
0.100 GeneticVariation BEFREE CCR2-64I and CXCL12 3'A alleles confer a favorable prognosis to AIDS patients undergoing HAART therapy. 16286054

2005

Entrez Id: 92345
Gene Symbol: NAF1
NAF1
CUI: C0001175
Disease: Acquired Immunodeficiency Syndrome
Acquired Immunodeficiency Syndrome
0.010 Biomarker BEFREE Naf1 also binds to Nef, which plays a key role in acquired immunodeficiency syndrome pathogenesis and HIV-1 virus replication. 17016622

2006

Entrez Id: 6962
Gene Symbol: TRBV20OR9-2
TRBV20OR9-2
CUI: C0001175
Disease: Acquired Immunodeficiency Syndrome
Acquired Immunodeficiency Syndrome
0.020 Biomarker BEFREE TCR usage may significantly influence CD8+ T cell-mediated control of AIDS viruses; however, the potential to modulate the repertoire of functional virus-specific T cells by immunotherapy has not been explored. 17579081

2007

Entrez Id: 3105
Gene Symbol: HLA-A
HLA-A
CUI: C0001175
Disease: Acquired Immunodeficiency Syndrome
Acquired Immunodeficiency Syndrome
0.050 Biomarker BEFREE HLA-A or B and HLA-Bw6-Bw6 homozygotes were also overrepresented in the AIDS patients group. 19703245

2009

Entrez Id: 2152
Gene Symbol: F3
F3
CUI: C0001175
Disease: Acquired Immunodeficiency Syndrome
Acquired Immunodeficiency Syndrome
0.020 AlteredExpression BEFREE Tissue factor (TF) is a molecular marker that is up-regulated in cancer cells and aids tumoral dissemination. 21128872

2011

Entrez Id: 1234
Gene Symbol: CCR5
CCR5
CUI: C0001175
Disease: Acquired Immunodeficiency Syndrome
Acquired Immunodeficiency Syndrome
0.100 Biomarker BEFREE CCR5-Δ32 was associated with a reduction in the risk for CD4+ T-cell depletion and with an increased risk for death after AIDS diagnosis. 21739027

2011

Entrez Id: 729230
Gene Symbol: CCR2
CCR2
CUI: C0001175
Disease: Acquired Immunodeficiency Syndrome
Acquired Immunodeficiency Syndrome
0.100 Biomarker BEFREE CCR2-64I was associated with a reduction in the risk for developing AIDS. 21739027

2011

Entrez Id: 6387
Gene Symbol: CXCL12
CXCL12
CUI: C0001175
Disease: Acquired Immunodeficiency Syndrome
Acquired Immunodeficiency Syndrome
0.100 GeneticVariation BEFREE SDF1-3'A was also associated with decreased risk for AIDS, but its effect was only evident when CCR2-64I was present as well. 21739027

2011

Entrez Id: 6898
Gene Symbol: TAT
TAT
CUI: C0001175
Disease: Acquired Immunodeficiency Syndrome
Acquired Immunodeficiency Syndrome
0.070 Biomarker BEFREE Tat protein of HIV-1 stimulates growth of cells derived from Kaposi's sarcoma lesions of AIDS patients. 2184372

1990

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0001175
Disease: Acquired Immunodeficiency Syndrome
Acquired Immunodeficiency Syndrome
0.020 GeneticVariation BEFREE ABCB1 variation and treatment response in AIDS patients: initial results of the Henan cohort. 23372834

2013

Entrez Id: 3575
Gene Symbol: IL7R
IL7R
CUI: C0001175
Disease: Acquired Immunodeficiency Syndrome
Acquired Immunodeficiency Syndrome
0.010 GeneticVariation BEFREE Interleukin-7 receptor gene polymorphism at +1237 locus and its effect on susceptibility to opportunistic infections among HIV and AIDS patients in Limpopo Province, South Africa. 25366767

2014

Entrez Id: 929
Gene Symbol: CD14
CD14
CUI: C0001175
Disease: Acquired Immunodeficiency Syndrome
Acquired Immunodeficiency Syndrome
0.010 Biomarker BEFREE CD14(+) macrophages that accumulate in the colon of African AIDS patients express pro-inflammatory cytokines and are responsive to lipopolysaccharide. 26475133

2015

Entrez Id: 30816
Gene Symbol: ERVW-1
ERVW-1
CUI: C0001175
Disease: Acquired Immunodeficiency Syndrome
Acquired Immunodeficiency Syndrome
0.100 Biomarker BEFREE Envelope glycoprotein purified from culture fluids was immunogenic in laboratory animals in both native and PAGE-purified forms and was reactive with AIDS patient sera in immunoassays. 2833915

1987

Entrez Id: 100616444
Gene Symbol: ERVK-20
ERVK-20
CUI: C0001175
Disease: Acquired Immunodeficiency Syndrome
Acquired Immunodeficiency Syndrome
0.100 Biomarker BEFREE Envelope glycoprotein purified from culture fluids was immunogenic in laboratory animals in both native and PAGE-purified forms and was reactive with AIDS patient sera in immunoassays. 2833915

1987

Entrez Id: 64006
Gene Symbol: ERVK-6
ERVK-6
CUI: C0001175
Disease: Acquired Immunodeficiency Syndrome
Acquired Immunodeficiency Syndrome
0.060 Biomarker BEFREE Envelope glycoprotein purified from culture fluids was immunogenic in laboratory animals in both native and PAGE-purified forms and was reactive with AIDS patient sera in immunoassays. 2833915

1987

Entrez Id: 283420
Gene Symbol: CLEC9A
CLEC9A
CUI: C0001175
Disease: Acquired Immunodeficiency Syndrome
Acquired Immunodeficiency Syndrome
0.010 AlteredExpression BEFREE DNGR-1 transcription levels were also significantly reduced in the blood of ART-treated AIDS patients irrespective of viral status. 28478499

2017