×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
CD44 -positive cancer stem cells expressing cellular prion protein contribute to metastatic capacity in colorectal cancer .23418321 2013
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
AlteredExpression
BEFREE
CD44 expression in intestinal epithelium and colorectal cancer is independent of p53 status.24009708 2013
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
CD44 -SLC1A2 fusion transcripts in primary colorectal cancer .25576211 2015
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
AlteredExpression
BEFREE
CD44 and CD133 mRNA were highly correlatively co-expressed in colorectal cancer with hepatic metastases.25625240 2015
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
CD44 epithelial isoform inversely associates with invasive characteristics of colorectal cancer .30942083 2019
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
CD44 splice variants as prognostic markers in colorectal cancer .9489913 1998
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
Abnormal expression of the variant exons and of intron 9 of the CD44 gene in tumour cells exfoliated into the colonic lumen may be helpful markers for the early, non-invasive, diagnosis of colorectal cancer .
8655705 1996
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
AlteredExpression
BEFREE
Activation of c-Met and upregulation of CD44 expression are associated with the metastatic phenotype in the colorectal cancer liver metastasis model.
24823486 2014
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
Alternatively spliced variants of the cell adhesion molecule CD44 and tumour progression in colorectal cancer .
8695347 1996
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
An RNA-immunoprecipitation analysis showed Hnrnpll-binding to <i>Cd44</i> pre-mRNAs, and the level of <i>Cd44 variable exon 6</i> (<i>Cd44v6</i>)<i>,</i> a poor prognosis marker of colorectal cancer , was increased by knocking down <i>Hnrnpll</i>.
28360095 2018
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
As CD133 and CD44 are notable markers of cancer stem cells (CSCs) identity, it is thought to be a predictive indicator for colorectal cancer .
30799951 2019
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
Association of CD44 gene rs187115 polymorphism with colorectal cancer risk and prognosis in Chinese Han population: a case-control study.
31682231 2019
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
Based on the important role of CD44 splice variants in colorectal cancer progression and metastasis, we evaluated the use of CD44v6 expression to detect and assess the metastatic potential of colorectal tumour cells circulating in peripheral blood.
10755402 2000
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
AlteredExpression
BEFREE
Cancer stem cell marker in circulating tumor cells: expression of CD44 variant exon 9 is strongly correlated to treatment refractoriness, recurrence and prognosis of human colorectal cancer .
25550556 2015
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
AlteredExpression
BEFREE
Clinical significance of serum levels of CD44 variant exons 8-10 protein in colorectal cancer .
9658313 1998
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
AlteredExpression
BEFREE
Comparison of cyclooxygenase-2 and CD44 mRNA expression in colorectal cancer and its relevance for prognosis.
19277703 2009
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
AlteredExpression
BEFREE
Concurrent Expression of CD47 and CD44 in Colorectal Cancer Promotes Malignancy.
31132784 2019
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
AlteredExpression
BEFREE
Deranged CD44 gene activity in colorectal cancer cells is confirmed.
9117309 1997
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
Epithelial to mesenchymal transition might be induced via CD44 isoform switching in colorectal cancer .
24975268 2014
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
Expression of a CD44 variant containing exons 8 to 10 is a useful independent factor for the prediction of prognosis in colorectal cancer patients.
8648366 1996
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
Functional Genetic Variations at the microRNA Binding-Site in the CD44 Gene Are Associated with Risk of Colorectal Cancer in Chinese Populations.
26010608 2015
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
AlteredExpression
BEFREE
Further mechanistic studies suggest that TRIM29 can activate the Wnt/β-catenin signaling pathway via up-regulating CD44 expression in colorectal cancer .
30813948 2019
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
Furthermore, we report a unique roster of all expressed CD44 variant isoforms characteristic to colorectal cancer .
23151220 2012
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
Here we report a functional role for CD44 variant isoforms in colorectal cancer metastasis.
9721884 1998
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
Human colorectal cancer -derived carcinoma associated fibroblasts promote CD44 -mediated adhesion of colorectal cancer cells to endothelial cells by secretion of HGF.
31367190 2019