×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
Epithelial to mesenchymal transition might be induced via CD44 isoform switching in colorectal cancer .
24975268 2014
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
Association of CD44 gene rs187115 polymorphism with colorectal cancer risk and prognosis in Chinese Han population: a case-control study.
31682231 2019
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
AlteredExpression
BEFREE
Activation of c-Met and upregulation of CD44 expression are associated with the metastatic phenotype in the colorectal cancer liver metastasis model.
24823486 2014
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
Thus, we are hopeful that anti-CD44 therapy will be applied in the treatment of colorectal cancer in the future.
30631039 2019
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
OPN, MAPK, MDM2, P53, PEDF and CD44 may act as osteogenic factors in colorectal cancer with OM.
29029440 2017
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
AlteredExpression
BEFREE
Cancer stem cell marker in circulating tumor cells: expression of CD44 variant exon 9 is strongly correlated to treatment refractoriness, recurrence and prognosis of human colorectal cancer .
25550556 2015
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
In this study, we established a CD44 (+) colorectal cancer stem cell line with particular emphasis on its self-renewal capacity, enhanced tumor initiation and drug resistance.
23736004 2013
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
The Prognostic and Clinical Value of CD44 in Colorectal Cancer : A Meta-Analysis.
31114754 2019
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
Furthermore, we report a unique roster of all expressed CD44 variant isoforms characteristic to colorectal cancer .
23151220 2012
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
These results suggest that CD44 and CD133 could be strong markers of colorectal cancer stem cells.
26840024 2016
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
AlteredExpression
BEFREE
CD44 and CD133 mRNA were highly correlatively co-expressed in colorectal cancer with hepatic metastases.25625240 2015
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
CD44 -SLC1A2 fusion transcripts in primary colorectal cancer .25576211 2015
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
Immunohistochemistry was performed to investigate the clinical importance of CD44 s and CD44v6 and their relevance to EMT in 113 patients with stage II/III colorectal cancer treated by curative resection.
23404221 2013
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
The results of this study show that mutant p53 protein and variant v6 of the CD44 glycoprotein are markers of tumour progression in colorectal cancer .
7534253 1995
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
CD44 epithelial isoform inversely associates with invasive characteristics of colorectal cancer .30942083 2019
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
Here we report a functional role for CD44 variant isoforms in colorectal cancer metastasis.
9721884 1998
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
Reciprocal interactions between tumor-associated macrophages and CD44 -positive cancer cells via osteopontin/CD44 promote tumorigenicity in colorectal cancer .
23251004 2013
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
Long Non-Coding RNA ucoo2kmd.1 Regulates CD44 -Dependent Cell Growth by Competing for miR-211-3p in Colorectal Cancer .
26974151 2016
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
An RNA-immunoprecipitation analysis showed Hnrnpll-binding to <i>Cd44</i> pre-mRNAs, and the level of <i>Cd44 variable exon 6</i> (<i>Cd44v6</i>)<i>,</i> a poor prognosis marker of colorectal cancer , was increased by knocking down <i>Hnrnpll</i>.
28360095 2018
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
Biomarker
BEFREE
Our findings provide rationale for targeting signaling via MET and CD44 during anti-EGF receptor therapy of patients with colorectal cancer or in patients resistant to EGF receptor inhibitors.
28716720 2017
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
AlteredExpression
BEFREE
The significance of CD44 variants expression in colorectal cancer and its regional lymph nodes.
11194197 2000
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
AlteredExpression
BEFREE
Multivariate analysis demonstrated that CD44 expression and lymph node metastasis in gastric cancer and CD44 and sialyl Lea expression in colorectal cancer were significantly related to hepatic metastasis.
9772282 1998
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
GeneticVariation
BEFREE
Functional Genetic Variations at the microRNA Binding-Site in the CD44 Gene Are Associated with Risk of Colorectal Cancer in Chinese Populations.
26010608 2015
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
AlteredExpression
BEFREE
Comparison of cyclooxygenase-2 and CD44 mRNA expression in colorectal cancer and its relevance for prognosis.
19277703 2009
×
Entrez Id: 960
Gene Symbol: CD44
CD44
Malignant neoplasm of colon and/or rectum
0.100
AlteredExpression
BEFREE
The expression of alternatively spliced CD44 adhesion molecules has been implicated in the pathogenesis and metastasis of colorectal cancer .
9849461 1998