Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7421
Gene Symbol: VDR
VDR
CUI: C0221775
Disease: Lumbar disc disease
Lumbar disc disease 		0.060 GeneticVariation BEFREE The VDR AA homozygous genotype was seen in 30(16.7%) patients with LDD and 20(8.7%) controls (codominant model: OR = 2.48; 95% CI 1.30-4.73, P = .005) with an estimated approximately 2.5-fold risk of developing LDD in individuals with this genotype. 29316495

2018
Entrez Id: 7421
Gene Symbol: VDR
VDR
CUI: C0221775
Disease: Lumbar disc disease
Lumbar disc disease 		0.060 Biomarker BEFREE LDD is closely associated in occurrence and severity with occupational, environmental risk factors and susceptibility genes namely MMP-3, and VDR (ApaI). 23975061

2014
Entrez Id: 7421
Gene Symbol: VDR
VDR
CUI: C0221775
Disease: Lumbar disc disease
Lumbar disc disease 		0.060 GeneticVariation BEFREE We investigated the association between vitamin-D receptor gene and estrogen receptor gene polymorphisms and lumbar disc disease in young adults. 12429765

2002
Entrez Id: 7421
Gene Symbol: VDR
VDR
CUI: C0221775
Disease: Lumbar disc disease
Lumbar disc disease 		0.060 GeneticVariation BEFREE Based on our results, VDR and its gene variants are highly associated with specific degenerative LDD endophenotypes. 31768839

2020
Entrez Id: 7421
Gene Symbol: VDR
VDR
CUI: C0221775
Disease: Lumbar disc disease
Lumbar disc disease 		0.060 AlteredExpression BEFREE Plasma VDR levels and VDR expression were significantly lower in patients with LDD compared with controls (all P < 0.05). 31127184

2019
Entrez Id: 7421
Gene Symbol: VDR
VDR
CUI: C0221775
Disease: Lumbar disc disease
Lumbar disc disease 		0.060 GeneticVariation BEFREE There was no evidence that the VDR gene polymorphisms (TaqI, FokI, ApaI) had significant associations with LDD risk. 27613009

2017