Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2239
Gene Symbol: GPC4
GPC4
CUI: C4021343
Disease: Broad hallux phalanx
Broad hallux phalanx
0.100 Biomarker HPO

Entrez Id: 2239
Gene Symbol: GPC4
GPC4
CUI: C1839276
Disease: Broad secondary alveolar ridge
Broad secondary alveolar ridge
0.100 Biomarker HPO

Entrez Id: 2239
Gene Symbol: GPC4
GPC4
CUI: C0426891
Disease: Broad thumbs
Broad thumbs
0.100 Biomarker HPO

Entrez Id: 2239
Gene Symbol: GPC4
GPC4
CUI: C1865038
Disease: Broad toe
Broad toe
0.100 Biomarker HPO

Entrez Id: 2239
Gene Symbol: GPC4
GPC4
CUI: C0006384
Disease: Bundle-Branch Block
Bundle-Branch Block
0.100 Biomarker HPO

Entrez Id: 2239
Gene Symbol: GPC4
GPC4
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
0.010 Biomarker BEFREE CD36 inhibits β-catenin/c-myc-mediated glycolysis through ubiquitination of GPC4 to repress colorectal tumorigenesis. 31484922

2019

Entrez Id: 2239
Gene Symbol: GPC4
GPC4
CUI: C0003811
Disease: Cardiac Arrhythmia
Cardiac Arrhythmia
0.100 Biomarker HPO

Entrez Id: 2239
Gene Symbol: GPC4
GPC4
CUI: C0878544
Disease: Cardiomyopathies
Cardiomyopathies
0.100 Biomarker HPO

Entrez Id: 2239
Gene Symbol: GPC4
GPC4
CUI: C1840379
Disease: Cerebellar vermis hypoplasia
Cerebellar vermis hypoplasia
0.100 Biomarker HPO

Entrez Id: 2239
Gene Symbol: GPC4
GPC4
CUI: C0158779
Disease: Cervical rib
Cervical rib
0.100 Biomarker HPO

Entrez Id: 2239
Gene Symbol: GPC4
GPC4
CUI: C2347762
Disease: Childhood Teratoma
Childhood Teratoma
0.010 Biomarker BEFREE Reducing glypican-4 in ES cells improves recovery in a rat model of Parkinson's disease by increasing the production of dopaminergic neurons and decreasing teratoma formation. 24920634

2014

Entrez Id: 2239
Gene Symbol: GPC4
GPC4
CUI: C0399526
Disease: Class III malocclusion
Class III malocclusion
0.100 Biomarker HPO

Entrez Id: 2239
Gene Symbol: GPC4
GPC4
CUI: C0008925
Disease: Cleft Palate
Cleft Palate
0.100 Biomarker HPO

Entrez Id: 2239
Gene Symbol: GPC4
GPC4
CUI: C0008924
Disease: Cleft upper lip
Cleft upper lip
0.100 Biomarker HPO

Entrez Id: 2239
Gene Symbol: GPC4
GPC4
CUI: C4551485
Disease: Clinodactyly
Clinodactyly
0.100 Biomarker HPO

Entrez Id: 2239
Gene Symbol: GPC4
GPC4
CUI: C0265610
Disease: Clinodactyly of fingers
Clinodactyly of fingers
0.100 Biomarker HPO

Entrez Id: 2239
Gene Symbol: GPC4
GPC4
CUI: C1850049
Disease: Clinodactyly of the 5th finger
Clinodactyly of the 5th finger
0.100 Biomarker HPO

Entrez Id: 2239
Gene Symbol: GPC4
GPC4
CUI: C1845847
Disease: Coarse facial features
Coarse facial features
0.100 Biomarker HPO

Entrez Id: 2239
Gene Symbol: GPC4
GPC4
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.010 Biomarker BEFREE Our results reveal a CD36-GPC4-β-catenin-c-myc signaling axis that regulates glycolysis in CRC development and may provide an intervention strategy for CRC prevention. 31484922

2019

Entrez Id: 2239
Gene Symbol: GPC4
GPC4
CUI: C0000768
Disease: Congenital Abnormality
Congenital Abnormality
0.010 Biomarker BEFREE Glypican-4 (GPC4) is one of the members of the glypicans family, which underlies human congenital malformations and multiple diseases. 30010221

2018

Entrez Id: 2239
Gene Symbol: GPC4
GPC4
CUI: C0009081
Disease: Congenital clubfoot
Congenital clubfoot
0.100 Biomarker HPO

Entrez Id: 2239
Gene Symbol: GPC4
GPC4
CUI: C0235833
Disease: Congenital diaphragmatic hernia
Congenital diaphragmatic hernia
0.100 Biomarker HPO

Entrez Id: 2239
Gene Symbol: GPC4
GPC4
CUI: C4551649
Disease: Congenital Dysplasia Of The Hip
Congenital Dysplasia Of The Hip
0.100 Biomarker HPO

Entrez Id: 2239
Gene Symbol: GPC4
GPC4
CUI: C0678230
Disease: Congenital Epicanthus
Congenital Epicanthus
0.100 Biomarker HPO

Entrez Id: 2239
Gene Symbol: GPC4
GPC4
CUI: C1306503
Disease: Congenital exomphalos
Congenital exomphalos
0.100 Biomarker HPO