Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix 		0.100 AlteredExpression BEFREE Additionally, treatment with butein significantly increased reactive oxygen species (ROS) generation and reduced the phosphorylation of PI3K, AKT and mTOR expression, which contributes to the inhibition of the tumor growth of cervical cancer and reduction of oxidative stress. 25962638

2015
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix 		0.100 GeneticVariation BEFREE Here we demonstrate that PTEN destabilization is induced by EGFR- or oncogenic PI3K mutation-mediated AKT activation in cervical cancer. 26183061

2015
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix 		0.100 Biomarker BEFREE Taken together, our data suggest that anti-VEGFa treatment in cervical cancer may inhibit both tumor cell growth and invasion through PI3k/Akt/mTor signaling pathway. 25135429

2014
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix 		0.100 Biomarker BEFREE CD38 was correlated with dysregulation of the phosphatidylinositol 3-kinase (PI3K)/Akt signaling pathway in cervical cancer tissues in vitro. 25310288

2014
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix 		0.100 Biomarker BEFREE These results suggest that targeted inhibition of PI3K/AKT may improve response to chemoradiation in cervical cancer. 23899375

2013
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix 		0.100 Biomarker BEFREE Activation of the PI3K/Akt pathway is associated with incomplete metabolic response in cervical cancer. 22235101

2012
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix 		0.100 AlteredExpression BEFREE Combination of valproic acid and ATRA restores RARβ2 expression and induces differentiation in cervical cancer through the PI3K/Akt pathway. 22229477

2012
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix 		0.100 Biomarker BEFREE Stathmin is involved in arsenic trioxide-induced apoptosis in human cervical cancer cell lines via PI3K linked signal pathway. 20657188

2010