×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Mutationally activated K-ras 4A and 4B both mediate lung carcinogenesis.
18062963 2008
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Genetically engineered murine models of mutant EGFR and KRAS have been developed that more accurately recapitulate human lung cancer .
18927287 2008
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Lung cancer in never smokers: a review.
17290066 2007
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Downregulation of RECK by promoter methylation correlates with lymph node metastasis in non-small cell lung cancer.
17233834 2007
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
K-ras mutations in lung tumors and tumors from other organs are consistent with a common mechanism of ethylene oxide tumorigenesis in the B6C3F1 mouse.
17325976 2007
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Genetic alterations in cancer knowledge system: analysis of gene mutations in mouse and human liver and lung tumors.
16410370 2006
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
A mouse model for tumor progression of lung cancer in ras and p53 transgenic mice.
16247444 2006
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
A functional switch from lung cancer resistance to susceptibility at the Pas1 locus in Kras2LA2 mice.
16823377 2006
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Gene expression analysis of urethane-induced lung tumors in ras H2 mice.
16289808 2006
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Codon 12 region of mouse K-ras gene is the site for in vitro binding of transcription factors GATA-6 and NF-Y.
16271038 2005
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Decrease in K-ras p21 and increase in Raf1 and activated Erk 1 and 2 in murine lung tumors initiated by N-nitrosodimethylamine and promoted by 2,3,7,8-tetrachlorodibenzo-p-dioxin.
11884234 2002
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Map kinase activation correlates with K-ras mutation and loss of heterozygosity on chromosome 6 in alveolar bronchiolar carcinomas from B6C3F1 mice exposed to vanadium pentoxide for 2 years.
12376484 2002
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Heterozygous inactivation of TGF-beta1 increases the susceptibility to chemically induced mouse lung tumorigenesis independently of mutational activation of K-ras.
11641043 2001
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Cigarette smoking is strongly associated with mutation of the K-ras gene in patients with primary adenocarcinoma of the lung.
11745231 2001
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
[K-ras gene mutations of asbestos and welding-fumes related human lung cancer ].
12725029 2000
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
DNA adduct measurements, cell proliferation and tumor mutation induction in relation to tumor formation in B6C3F1 mice fed coal tar or benzo[a]pyrene.
10874023 2000
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
High frequency of codon 61 K-ras A-->T transversions in lung and Harderian gland neoplasms of B6C3F1 mice exposed to chloroprene (2-chloro-1,3-butadiene) for 2 years, and comparisons with the structurally related chemicals isoprene and 1,3-butadiene.
10223196 1999
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Strain-dependent lung tumor formation in mice transplacentally exposed to 3-methylcholanthrene and post-natally exposed to butylated hydroxytoluene.
10545420 1999
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Benzo[b]fluoranthene: tumorigenicity in strain A/J mouse lungs, DNA adducts and mutations in the Ki-ras oncogene.
8761429 1996
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Increased frequency of K-ras mutations in lung neoplasms from female B6C3F1 mice exposed to ozone for 24 or 30 months.
7614698 1995
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Long-term toxicity studies of ozone in F344/N rats and B6C3F1 mice.
8597069 1995
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
Mutations of the Ki-ras protooncogene in 3-methylcholanthrene and urethan-induced and butylated hydroxytoluene-promoted lung tumors of strain A/J and SWR mice.
7750092 1995
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
Biomarker
CTD_human
K-ras mutations in benzotrichloride-induced lung tumors of A/J mice.
8508514 1993
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
CausalMutation
CGI
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Malignant neoplasm of lung
0.700
GeneticVariation
UNIPROT