Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3242
Gene Symbol: HPD
HPD
CUI: C4279912
Disease: Chemically-Induced Liver Toxicity
Chemically-Induced Liver Toxicity
0.300 Biomarker CTD_human A performance evaluation of three drug-induced liver injury biomarkers in the rat: alpha-glutathione S-transferase, arginase 1, and 4-hydroxyphenyl-pyruvate dioxygenase. 22872058

2012

Entrez Id: 51056
Gene Symbol: LAP3
LAP3
CUI: C4279912
Disease: Chemically-Induced Liver Toxicity
Chemically-Induced Liver Toxicity
0.300 Biomarker CTD_human Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model. 25231249

2015

Entrez Id: 406935
Gene Symbol: MIR143
MIR143
CUI: C4279912
Disease: Chemically-Induced Liver Toxicity
Chemically-Induced Liver Toxicity
0.300 Biomarker CTD_human Identification of Specific MicroRNA Biomarkers in Early Stages of Hepatocellular Injury, Cholestasis, and Steatosis in Rats. 30125006

2018

Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C4279912
Disease: Chemically-Induced Liver Toxicity
Chemically-Induced Liver Toxicity
0.300 Biomarker CTD_human Trovafloxacin enhances TNF-induced inflammatory stress and cell death signaling and reduces TNF clearance in a murine model of idiosyncratic hepatotoxicity. 19638433

2009

Entrez Id: 406884
Gene Symbol: MIRLET7B
MIRLET7B
CUI: C4279912
Disease: Chemically-Induced Liver Toxicity
Chemically-Induced Liver Toxicity
0.300 Biomarker CTD_human "Serum microRNA signatures as ""liquid biopsies"" for interrogating hepatotoxic mechanisms and liver pathogenesis in human." 28545106

2017

Entrez Id: 442909
Gene Symbol: MIR342
MIR342
CUI: C4279912
Disease: Chemically-Induced Liver Toxicity
Chemically-Induced Liver Toxicity
0.300 Biomarker CTD_human "Serum microRNA signatures as ""liquid biopsies"" for interrogating hepatotoxic mechanisms and liver pathogenesis in human." 28545106

2017

Entrez Id: 10
Gene Symbol: NAT2
NAT2
CUI: C4279912
Disease: Chemically-Induced Liver Toxicity
Chemically-Induced Liver Toxicity
0.300 Biomarker CTD_human Polymorphism of the N-acetyltransferase 2 gene as a susceptibility risk factor for antituberculosis drug-induced hepatitis. 11915035

2002

Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C4279912
Disease: Chemically-Induced Liver Toxicity
Chemically-Induced Liver Toxicity
0.300 Therapeutic CTD_human Amiodarone exposure during modest inflammation induces idiosyncrasy-like liver injury in rats: role of tumor necrosis factor-alpha. 21984482

2012

Entrez Id: 406906
Gene Symbol: MIR122
MIR122
CUI: C4279912
Disease: Chemically-Induced Liver Toxicity
Chemically-Induced Liver Toxicity
0.300 Biomarker CTD_human MicroRNA-122: a novel hepatocyte-enriched in vitro marker of drug-induced cellular toxicity. 25527335

2015

Entrez Id: 407026
Gene Symbol: MIR29C
MIR29C
CUI: C4279912
Disease: Chemically-Induced Liver Toxicity
Chemically-Induced Liver Toxicity
0.300 Biomarker CTD_human Embracing the Dark Side: Computational Approaches to Unveil the Functionality of Genes Lacking Biological Annotation in Drug-Induced Liver Injury. 30515189

2018

Entrez Id: 23476
Gene Symbol: BRD4
BRD4
CUI: C4279912
Disease: Chemically-Induced Liver Toxicity
Chemically-Induced Liver Toxicity
0.300 Biomarker CTD_human Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model. 25231249

2015

Entrez Id: 5236
Gene Symbol: PGM1
PGM1
CUI: C4279912
Disease: Chemically-Induced Liver Toxicity
Chemically-Induced Liver Toxicity
0.300 Biomarker CTD_human Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model. 25231249

2015

Entrez Id: 5053
Gene Symbol: PAH
PAH
CUI: C4279912
Disease: Chemically-Induced Liver Toxicity
Chemically-Induced Liver Toxicity
0.300 Biomarker CTD_human Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model. 25231249

2015

Entrez Id: 6648
Gene Symbol: SOD2
SOD2
CUI: C4279912
Disease: Chemically-Induced Liver Toxicity
Chemically-Induced Liver Toxicity
0.300 Biomarker CTD_human Characterization of chemically induced liver injuries using gene co-expression modules. 25226513

2014

Entrez Id: 3708
Gene Symbol: ITPR1
ITPR1
CUI: C4279912
Disease: Chemically-Induced Liver Toxicity
Chemically-Induced Liver Toxicity
0.300 Biomarker CTD_human Characterization of chemically induced liver injuries using gene co-expression modules. 25226513

2014

Entrez Id: 1244
Gene Symbol: ABCC2
ABCC2
CUI: C4279912
Disease: Chemically-Induced Liver Toxicity
Chemically-Induced Liver Toxicity
0.300 Biomarker CTD_human Defining targets for investigating the pharmacogenomics of adverse drug reactions to antifungal agents. 18466103

2008

Entrez Id: 9970
Gene Symbol: NR1I3
NR1I3
CUI: C4279912
Disease: Chemically-Induced Liver Toxicity
Chemically-Induced Liver Toxicity
0.300 Biomarker CTD_human Involvement of constitutive androstane receptor in liver hypertrophy and liver tumor development induced by triazole fungicides. 25656644

2015

Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
CUI: C4279912
Disease: Chemically-Induced Liver Toxicity
Chemically-Induced Liver Toxicity
0.300 Therapeutic CTD_human Role of Nrf2 in preventing ethanol-induced oxidative stress and lipid accumulation. 22627062

2012

Entrez Id: 406906
Gene Symbol: MIR122
MIR122
CUI: C4279912
Disease: Chemically-Induced Liver Toxicity
Chemically-Induced Liver Toxicity
0.300 Biomarker CTD_human Comprehensive microRNA profiling in acetaminophen toxicity identifies novel circulating biomarkers for human liver and kidney injury. 26489516

2015

Entrez Id: 3030
Gene Symbol: HADHA
HADHA
CUI: C4279912
Disease: Chemically-Induced Liver Toxicity
Chemically-Induced Liver Toxicity
0.300 Biomarker CTD_human Characterization of chemically induced liver injuries using gene co-expression modules. 25226513

2014

Entrez Id: 5436
Gene Symbol: POLR2G
POLR2G
CUI: C4279912
Disease: Chemically-Induced Liver Toxicity
Chemically-Induced Liver Toxicity
0.300 Biomarker CTD_human Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model. 25231249

2015

Entrez Id: 3242
Gene Symbol: HPD
HPD
CUI: C4279912
Disease: Chemically-Induced Liver Toxicity
Chemically-Induced Liver Toxicity
0.300 Biomarker CTD_human Use of proteomic methods to identify serum biomarkers associated with rat liver toxicity or hypertrophy. 16099942

2005

Entrez Id: 10989
Gene Symbol: IMMT
IMMT
CUI: C4279912
Disease: Chemically-Induced Liver Toxicity
Chemically-Induced Liver Toxicity
0.300 Biomarker CTD_human Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model. 25231249

2015

Entrez Id: 406933
Gene Symbol: MIR141
MIR141
CUI: C4279912
Disease: Chemically-Induced Liver Toxicity
Chemically-Induced Liver Toxicity
0.300 Biomarker CTD_human "Serum microRNA signatures as ""liquid biopsies"" for interrogating hepatotoxic mechanisms and liver pathogenesis in human." 28545106

2017

Entrez Id: 10096
Gene Symbol: ACTR3
ACTR3
CUI: C4279912
Disease: Chemically-Induced Liver Toxicity
Chemically-Induced Liver Toxicity
0.300 Biomarker CTD_human Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model. 25231249

2015