Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5507
Gene Symbol: PPP1R3C
PPP1R3C
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 Biomarker BEFREE The aim of the present study was to establish whether in people struggling with cancer there is an association between the degree of PTG and the level of deliberate and intrusive ruminations, occurring soon after the diagnosis of disease and currently, and whether deliberate ruminations play a mediating role between intrusive ruminations and PTG. 31084411

2020

Entrez Id: 51371
Gene Symbol: POMP
POMP
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 Biomarker BEFREE The NRF3-POMP-20S proteasome axis has an entirely different effect on cancer than NRF2. 31742837

2020

Entrez Id: 9427
Gene Symbol: ECEL1
ECEL1
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 AlteredExpression BEFREE Two hundred sixty-seven young people with cancer (n =83 cancer patients receiving active treatment: n =174 cancer survivors, 57.1% >1 year since treatment completion) and 321 controls completed a health and lifestyle questionnaire which included validated measures of physical activity (PA) (Godin Leisure Time Exercise Questionnaire), diet (Dietary Instrument for Nutrition Education, DINE), smoking status, and alcohol consumption (AUDIT-C). 31144171

2020

Entrez Id: 83743
Gene Symbol: GRWD1
GRWD1
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 AlteredExpression BEFREE GRWD1 is overexpressed in several cancer cell lines, and GRWD1 overexpression confers tumorigenic potential in human cells. 31545368

2020

Entrez Id: 103021164
Gene Symbol: CASC21
CASC21
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 Biomarker BEFREE The aim of this study was to investigate the role of new lncRNA homo sapiens cancer susceptibility 21 (CASC21) in the cancer biology of colorectal cancer and explore the underlying mechanism. 31731190

2020

Entrez Id: 8668
Gene Symbol: EIF3I
EIF3I
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 Biomarker BEFREE Cancer Targeted Gene Therapy for Inhibition of Melanoma Lung Metastasis with eIF3i shRNA Loaded Liposomes. 31765158

2020

Entrez Id: 106144539
Gene Symbol: FOXD1-AS1
FOXD1-AS1
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 Biomarker BEFREE Altered activities of long noncoding RNAs (lncRNAs) have been associated with cancer development, and lncRNA FOXD1-AS1 (FOXD1-AS1) is the antisense transcript of the gene encoding for FOXD1, known for its role as an oncogene in several tumor types including glioma. 31102349

2020

Entrez Id: 904
Gene Symbol: CCNT1
CCNT1
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 Biomarker BEFREE CDK9/Cyclin T1 kinase is a protein kinase, indirectly involved in the cell cycle progression in the form of transcription elongation, CDK9 specific inhibitors may be a potential alternative treatment not only for cancer but also other life-threatening diseases. 31603123

2020

Entrez Id: 22868
Gene Symbol: FASTKD2
FASTKD2
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 Biomarker BEFREE Collectively, this study uncovered that FASTKD2 promoted cancer cell progression through upregulating Myc expression in pancreatic cancer. 31692063

2020

Entrez Id: 101927034
Gene Symbol: ROR1-AS1
ROR1-AS1
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 AlteredExpression BEFREE The Cancer Genome Atlas Liver Hepatocellular Carcinoma was used to analyze the expression of ROR1‑AS1 in liver cancer. 31746401

2020

Entrez Id: 100313824
Gene Symbol: MIR663B
MIR663B
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 AlteredExpression BEFREE MiR-663b has been demonstrated to be abnormally expressed in several cancer types and was involved in the progression of cancer. 31758392

2020

Entrez Id: 100616258
Gene Symbol: MIR4516
MIR4516
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 Biomarker BEFREE The stromal loss of miR-4516 promotes the FOSL1-dependent proliferation and malignancy of triple negative breast cancer. 31672492

2020

Entrez Id: 338340
Gene Symbol: MMS
MMS
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 Biomarker BEFREE The present Fe<sub>3</sub>O<sub>4</sub>@LEC-CUR-PLGA-MMS system demonstrated much better in vitro cytotoxicity, cellular morphological changes and moreover an ability to limit colony formation for A549 and HeLa S3 cancer cell lines than non-cancerous cells, and thus, should be further studied for a wide range of medical applications. 31830615

2020

Entrez Id: 54922
Gene Symbol: RASIP1
RASIP1
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 AlteredExpression BEFREE Using RNA-sequencing profiling, we showed that RAIN orchestrates the expression of a network of cancer-promoting transcription regulators, suggesting that RAIN affects cancer cell phenotype by coordinating the expression of a complex transcriptional network. 31624086

2020

Entrez Id: 9929
Gene Symbol: JOSD1
JOSD1
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 AlteredExpression BEFREE JOSD1 overexpression caused chemoresistance in gynaecological cancer by upregulating the MCL1 protein. 31043700

2020

Entrez Id: 199223
Gene Symbol: TTC21A
TTC21A
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 Biomarker BEFREE In addition, we explored the correlation between TTC21A and cancer immune infiltrates using CIBERSORT and "Correlation" module of GEPIA. 31812070

2020

Entrez Id: 693172
Gene Symbol: MIR587
MIR587
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 Biomarker BEFREE These characteristics suggest that <i>miR-587</i> is an important candidate for cancer therapy research. 31721529

2020

Entrez Id: 4800
Gene Symbol: NFYA
NFYA
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 AlteredExpression BEFREE The work represents a proof-of-principle that elevated levels of NF-YA, as found in some tumor types, helps altering cancer metabolic pathways. 31706909

2020

Entrez Id: 9569
Gene Symbol: GTF2IRD1
GTF2IRD1
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 Biomarker BEFREE We identified general transcription factor 2I repeat domain-containing protein 1 (GTF2IRD1) as a potential oncogene using a CRC dataset from The Cancer Genome Atlas with a bioinformatics approach. 31758608

2020

Entrez Id: 100188011
Gene Symbol: DIP
DIP
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 Biomarker BEFREE In this communication, we demonstrate that two ruthenium complexes previously reported by our group for their chemotherapeutic potential against cancer, namely [Ru(DIP)2(sq)](PF6) and [Ru(DIP)2(3-methoxysq)](PF6), where DIP is 4,7-diphenyl-1,10-phenanthroline, sq = semiquinonate and 3-methoxysq = 3-methoxysemiquinonate, form colloids in water-DMSO (1% v/v) mixtures that are invisible to the naked eyes. 31840945

2020

Entrez Id: 79660
Gene Symbol: PPP1R3B
PPP1R3B
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 Biomarker BEFREE The aim of the present study was to establish whether in people struggling with cancer there is an association between the degree of PTG and the level of deliberate and intrusive ruminations, occurring soon after the diagnosis of disease and currently, and whether deliberate ruminations play a mediating role between intrusive ruminations and PTG. 31084411

2020

Entrez Id: 6554
Gene Symbol: SLC10A1
SLC10A1
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 Biomarker BEFREE NTCP and ICG form an ideal reporter system with extensive applications in cancer biology, robust drug-drug interactions, and drug screening in HBV/HDV infections. 31140111

2020

Entrez Id: 10885
Gene Symbol: WDR3
WDR3
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 Biomarker BEFREE In this communication, we demonstrate that two ruthenium complexes previously reported by our group for their chemotherapeutic potential against cancer, namely [Ru(DIP)2(sq)](PF6) and [Ru(DIP)2(3-methoxysq)](PF6), where DIP is 4,7-diphenyl-1,10-phenanthroline, sq = semiquinonate and 3-methoxysq = 3-methoxysemiquinonate, form colloids in water-DMSO (1% v/v) mixtures that are invisible to the naked eyes. 31840945

2020

Entrez Id: 100302217
Gene Symbol: MIR1827
MIR1827
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 AlteredExpression BEFREE In this study, we found that the expression of miR-1827 was downregulated in lung adenocarcinoma, and its low expression was significantly correlated with the progression of lung adenocarcinoma and poor prognosis of patients. miR-1827 overexpression remarkably reduced the malignancy of primary lung adenocarcinoma cells in vitro. 31595558

2020

Entrez Id: 100506394
Gene Symbol: GAS6-DT
GAS6-DT
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 Biomarker BEFREE Long noncoding RNA (lncRNA) GAS6-AS2 serves as an oncogenic lncRNA in various types of human cancer. 31839366

2020