×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Identification of fifteen novel germline variants in the BRCA1 3'UTR reveals a variant in a breast cancer case that introduces a functional miR-103 target site.
22753153 2012
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Structure-based assessment of missense mutations in human BRCA1: implications for breast and ovarian cancer predisposition.
15172985 2004
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Identifying the effects of BRCA1 mutations on homologous recombination using cells that express endogenous wild-type BRCA1.
21372787 2011
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Next-generation sequencing of the BRCA1 and BRCA2 genes for the genetic diagnostics of hereditary breast and/or ovarian cancer.
25556971 2015
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
The BRCA1 ubiquitin ligase and homologous recombination repair.
21570976 2011
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Molecular analysis of the BRCA1 and BRCA2 genes in 32 breast and/or ovarian cancer Spanish families.
10755399 2000
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Prediction of mutant mRNA splice isoforms by information theory-based exon definition.
23348723 2013
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
"BRCA1/2 mutations appear embryo-lethal unless rescued by low (CGG n<26) FMR1 sub-genotypes: explanation for the ""BRCA paradox""?"
22984553 2012
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
BRCA1 and BRCA2 mutations in Danish families with hereditary breast and/or ovarian cancer.
18465347 2008
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Functional assays provide a robust tool for the clinical annotation of genetic variants of uncertain significance.
28781887 2016
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
A missense variant within BRCA1 exon 23 causing exon skipping.
20875879 2010
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Comparative in vitro and in silico analyses of variants in splicing regions of BRCA1 and BRCA2 genes and characterization of novel pathogenic mutations.
23451180 2013
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Identification of seven new BRCA1 germline mutations in Italian breast and breast/ovarian cancer families.
8968102 1996
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Multimodel assessment of BRCA1 mutations in Taiwanese (ethnic Chinese) women with early-onset, bilateral or familial breast cancer.
22277901 2012
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Identification of germline alterations in breast cancer predisposition genes among Malaysian breast cancer patients using panel testing.
26757417 2016
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Structural basis for cell cycle checkpoint control by the BRCA1-CtIP complex.
16101277 2005
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Structure-Function Of The Tumor Suppressor BRCA1.
22737296 2012
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Comprehensive genetic characterization of hereditary breast/ovarian cancer families from Slovakia.
21203900 2011
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Individualized iterative phenotyping for genome-wide analysis of loss-of-function mutations.
26046366 2015
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Targeting the DNA double strand breaks repair for cancer therapy.
20423312 2010
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
The P1812A and P25T BRCA1 and the 5164del4 BRCA2 mutations: occurrence in high-risk non-Ashkenazi Jews.
17020472 2006
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
BRCA1 sequence analysis in women at high risk for susceptibility mutations. Risk factor analysis and implications for genetic testing.
9333265 1997
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
A systematic genetic assessment of 1,433 sequence variants of unknown clinical significance in the BRCA1 and BRCA2 breast cancer-predisposition genes.
17924331 2007
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Identification of missense and truncating mutations in the BRCA1 gene in sporadic and familial breast and ovarian cancer.
9523200 1998
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Predictive Factors for BRCA1 and BRCA2 Genetic Testing in an Asian Clinic-Based Population.
26221963 2015