Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3645
Gene Symbol: INSRR
INSRR
CUI: C0086103
Disease: Decayed, Missing, and Filled Teeth
Decayed, Missing, and Filled Teeth
0.010 Biomarker BEFREE Adults aged 35-44 years old who were female (IRR: 1.15, 95% CI: 1.00-1.33, P = .047), had good oral health knowledge and attitudes (IRR: 1.30, 95% CI: 1.06-1.59, P = .011), perceived their oral health status as fair (IRR:1.51, 95% CI:1.24-1.85, P < .001) or poor/very poor (IRR:2.52, 95% CI:2.01-3.18, P < .001) and had a decayed, missing and filled teeth (DMFT) index >0 (IRR: 1.52, 95% CI: 1.11-2.09, P = .009) were more likely to report dental visits in the past 12 months. 31621099

2020

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0086103
Disease: Decayed, Missing, and Filled Teeth
Decayed, Missing, and Filled Teeth
0.010 AlteredExpression BEFREE In the mothers, salivary VEGF levels were correlated with DMFT (r = 0.35; p = .03), WC (r = 0.35; p = .02), and sugar intake (r = 0.32; p = .04). 29246654

2018

Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C0086103
Disease: Decayed, Missing, and Filled Teeth
Decayed, Missing, and Filled Teeth
0.010 AlteredExpression BEFREE Higher salivary IL-6 levels were also correlated with maternal DMFT (r = 0.45; p = .004) and WC (r = 0.32; p = .04). 29246654

2018

Entrez Id: 4589
Gene Symbol: MUC7
MUC7
CUI: C0086103
Disease: Decayed, Missing, and Filled Teeth
Decayed, Missing, and Filled Teeth
0.010 GeneticVariation BEFREE Statistical analysis did not show a significant correlation between genotypes of the MUC7 gene and DMFT and the Plaque Control Record index. 22706105

2012

Entrez Id: 765
Gene Symbol: CA6
CA6
CUI: C0086103
Disease: Decayed, Missing, and Filled Teeth
Decayed, Missing, and Filled Teeth
0.010 GeneticVariation BEFREE The purpose of this study was to analyze the allele and genotype distribution of three polymorphisms in the coding sequences of (CA6) gene and check for possible associations with salivary buffer capacity, number of decayed, missing, and filled teeth in deciduous and permanent teeth (dmft/DMFT, Decayed/Missing/Filled Teeth), plaque index (PI), and the plaque pH variation (DeltapH) in children aged 7-9 years. 19721466

2010

Entrez Id: 58503
Gene Symbol: OPRPN
OPRPN
CUI: C0086103
Disease: Decayed, Missing, and Filled Teeth
Decayed, Missing, and Filled Teeth
0.010 Biomarker BEFREE With regard to salivary proteins and DMFT index, subjects with higher DMFT indices presented significant reduction or absence of high-molecular-weight mucin glycoprotein-1 (MG1), low-molecular-weight mucin glycoprotein-2 (MG2), and acidic proline-rich protein-1 (PRP-1), differing from subjects with lower DMFT indices (p <or=0.001). 12459324

2003