Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0205697
Disease: Carcinoma, Spindle-Cell
Carcinoma, Spindle-Cell
0.370 Biomarker CTD_human Unventilated indoor coal-fired stoves in Guizhou province, China: cellular and genetic damage in villagers exposed to arsenic in food and air. 17450239

2007

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0205697
Disease: Carcinoma, Spindle-Cell
Carcinoma, Spindle-Cell
0.370 Biomarker CTD_human Human papillomavirus DNA and p53 status in penile carcinomas. 9626339

1998

Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0205697
Disease: Carcinoma, Spindle-Cell
Carcinoma, Spindle-Cell
0.360 Biomarker CTD_human SMAD4--molecular gladiator of the TGF-beta signaling is trampled upon by mutational insufficiency in colorectal carcinoma of Kashmiri population: an analysis with relation to KRAS proto-oncogene. 20565773

2010

Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0205697
Disease: Carcinoma, Spindle-Cell
Carcinoma, Spindle-Cell
0.360 Biomarker CTD_human Strain-dependent lung tumor formation in mice transplacentally exposed to 3-methylcholanthrene and post-natally exposed to butylated hydroxytoluene. 10545420

1999

Entrez Id: 4233
Gene Symbol: MET
MET
CUI: C0205697
Disease: Carcinoma, Spindle-Cell
Carcinoma, Spindle-Cell
0.340 Biomarker CTD_human HGF/c-Met pathway has a prominent role in mediating antiapoptotic signals through AKT in epithelial ovarian carcinoma. 20661229

2011

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0205697
Disease: Carcinoma, Spindle-Cell
Carcinoma, Spindle-Cell
0.340 Biomarker CTD_human DU145 human prostate carcinoma invasiveness is modulated by urokinase receptor (uPAR) downstream of epidermal growth factor receptor (EGFR) signaling. 15302576

2004

Entrez Id: 8626
Gene Symbol: TP63
TP63
CUI: C0205697
Disease: Carcinoma, Spindle-Cell
Carcinoma, Spindle-Cell
0.330 Biomarker CTD_human Arsenic suppresses cell survival via Pirh2-mediated proteasomal degradation of ΔNp63 protein. 23271742

2013

Entrez Id: 60
Gene Symbol: ACTB
ACTB
CUI: C0205697
Disease: Carcinoma, Spindle-Cell
Carcinoma, Spindle-Cell
0.320 Biomarker CTD_human Global gene expression profiling of chemically induced rat mammary gland carcinomas and adenomas. 16316942

2005

Entrez Id: 1674
Gene Symbol: DES
DES
CUI: C0205697
Disease: Carcinoma, Spindle-Cell
Carcinoma, Spindle-Cell
0.310 Biomarker CTD_human cDNA microarray profiling of rat mammary gland carcinomas induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 7,12-dimethylbenz[a]anthracene. 12376462

2002

Entrez Id: 3852
Gene Symbol: KRT5
KRT5
CUI: C0205697
Disease: Carcinoma, Spindle-Cell
Carcinoma, Spindle-Cell
0.310 Biomarker CTD_human cDNA microarray profiling of rat mammary gland carcinomas induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 7,12-dimethylbenz[a]anthracene. 12376462

2002

Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
CUI: C0205697
Disease: Carcinoma, Spindle-Cell
Carcinoma, Spindle-Cell
0.310 Biomarker CTD_human Reduced Brca1 protein expression in 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced rat mammary carcinomas. 12203372

2002

Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0205697
Disease: Carcinoma, Spindle-Cell
Carcinoma, Spindle-Cell
0.310 Therapeutic CTD_human Rapamycin potentiates transforming growth factor beta-induced growth arrest in nontransformed, oncogene-transformed, and human cancer cells. 12417722

2002

Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0205697
Disease: Carcinoma, Spindle-Cell
Carcinoma, Spindle-Cell
0.310 Biomarker CTD_human Infrequent mutation of Ha-ras and p53 in rat mammary carcinomas induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. 8185828

1994

Entrez Id: 387
Gene Symbol: RHOA
RHOA
CUI: C0205697
Disease: Carcinoma, Spindle-Cell
Carcinoma, Spindle-Cell
0.300 Biomarker CTD_human Recurrent gain-of-function mutations of RHOA in diffuse-type gastric carcinoma. 24816255

2014

Entrez Id: 11151
Gene Symbol: CORO1A
CORO1A
CUI: C0205697
Disease: Carcinoma, Spindle-Cell
Carcinoma, Spindle-Cell
0.300 Biomarker CTD_human Methylation silencing of angiopoietin-like 4 in rat and human mammary carcinomas. 21489049

2011

Entrez Id: 1786
Gene Symbol: DNMT1
DNMT1
CUI: C0205697
Disease: Carcinoma, Spindle-Cell
Carcinoma, Spindle-Cell
0.300 Biomarker CTD_human DNA methyltransferase 1 as a predictive biomarker and potential therapeutic target for chemotherapy in gastric cancer. 21458988

2011

Entrez Id: 140738
Gene Symbol: TMEM37
TMEM37
CUI: C0205697
Disease: Carcinoma, Spindle-Cell
Carcinoma, Spindle-Cell
0.300 Biomarker CTD_human Methylation silencing of angiopoietin-like 4 in rat and human mammary carcinomas. 21489049

2011

Entrez Id: 9540
Gene Symbol: TP53I3
TP53I3
CUI: C0205697
Disease: Carcinoma, Spindle-Cell
Carcinoma, Spindle-Cell
0.300 Biomarker CTD_human Methylation silencing of angiopoietin-like 4 in rat and human mammary carcinomas. 21489049

2011

Entrez Id: 4692
Gene Symbol: NDN
NDN
CUI: C0205697
Disease: Carcinoma, Spindle-Cell
Carcinoma, Spindle-Cell
0.300 Biomarker CTD_human Methylation silencing of angiopoietin-like 4 in rat and human mammary carcinomas. 21489049

2011

Entrez Id: 8725
Gene Symbol: URI1
URI1
CUI: C0205697
Disease: Carcinoma, Spindle-Cell
Carcinoma, Spindle-Cell
0.300 Biomarker CTD_human URI is an oncogene amplified in ovarian cancer cells and is required for their survival. 21397856

2011

Entrez Id: 51129
Gene Symbol: ANGPTL4
ANGPTL4
CUI: C0205697
Disease: Carcinoma, Spindle-Cell
Carcinoma, Spindle-Cell
0.300 Biomarker CTD_human Methylation silencing of angiopoietin-like 4 in rat and human mammary carcinomas. 21489049

2011

Entrez Id: 57007
Gene Symbol: ACKR3
ACKR3
CUI: C0205697
Disease: Carcinoma, Spindle-Cell
Carcinoma, Spindle-Cell
0.300 Biomarker CTD_human Alteration of CXCR7 expression mediated by TLR4 promotes tumor cell proliferation and migration in human colorectal carcinoma. 22180778

2011

Entrez Id: 23643
Gene Symbol: LY96
LY96
CUI: C0205697
Disease: Carcinoma, Spindle-Cell
Carcinoma, Spindle-Cell
0.300 Biomarker CTD_human Alteration of CXCR7 expression mediated by TLR4 promotes tumor cell proliferation and migration in human colorectal carcinoma. 22180778

2011

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0205697
Disease: Carcinoma, Spindle-Cell
Carcinoma, Spindle-Cell
0.300 Biomarker CTD_human Impact of ABCB1 C3435T polymorphism on lymph node regression in multimodality treatment of locally advanced esophageal cancer. 21332314

2011

Entrez Id: 7099
Gene Symbol: TLR4
TLR4
CUI: C0205697
Disease: Carcinoma, Spindle-Cell
Carcinoma, Spindle-Cell
0.300 Biomarker CTD_human Alteration of CXCR7 expression mediated by TLR4 promotes tumor cell proliferation and migration in human colorectal carcinoma. 22180778

2011