Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5741
Gene Symbol: PTH
PTH
CUI: C0242699
Disease: Bone Demineralization, Pathologic
Bone Demineralization, Pathologic
0.010 AlteredExpression BEFREE He was found to have multiple fractures and diffuse bone demineralization, with a marked elevation in serum ionized calcium (1.99 mmol/L) and elevated serum levels of intact PTH (1154 pg/mL); serum 25-hydroxyvitamin D was low, and fractional excretion of calcium was reduced. 24203066

2014

Entrez Id: 5744
Gene Symbol: PTHLH
PTHLH
CUI: C0242699
Disease: Bone Demineralization, Pathologic
Bone Demineralization, Pathologic
0.010 Biomarker BEFREE A shared mechanism among these physiological and pathological states is endocrine secretion of parathyroid hormone-related protein (PTHrP), which acts through osteoblasts to stimulate osteoclastic bone demineralization. 22318950

2012

Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C0242699
Disease: Bone Demineralization, Pathologic
Bone Demineralization, Pathologic
0.010 Biomarker BEFREE Microgravity induces prostaglandin E2 and interleukin-6 production in normal rat osteoblasts: role in bone demineralization. 8987571

1996