×
Entrez Id:
115825
Gene Symbol:
WDFY2
WDFY2
Malignant Neoplasms
0.030
Biomarker
BEFREE
Interestingly, to confirm that WDFY2 belongs to the p63 network of cancer regulation, we analysed the impact of WDFY2 alterations, by showing its frequent deletion in different types of tumours and suggesting its expression level as a prognostic biomarker.
31789342
2019
×
Entrez Id:
115825
Gene Symbol:
WDFY2
WDFY2
Neoplasms
0.030
Biomarker
BEFREE
We propose that WDFY2 acts as a tumor suppressor by serving as a gatekeeper for VAMP3 recycling.
31253801
2019
×
Entrez Id:
115825
Gene Symbol:
WDFY2
WDFY2
Primary malignant neoplasm
0.030
Biomarker
BEFREE
Interestingly, to confirm that WDFY2 belongs to the p63 network of cancer regulation, we analysed the impact of WDFY2 alterations, by showing its frequent deletion in different types of tumours and suggesting its expression level as a prognostic biomarker.
31789342
2019
×
Entrez Id:
115825
Gene Symbol:
WDFY2
WDFY2
Malignant Neoplasms
0.030
AlteredExpression
BEFREE
Overexpression of WDFY2 in prostate cancer cells DU145 and PC-3 led to the suppression of cancer cell migration and colony formation.
28653900
2017
×
Entrez Id:
115825
Gene Symbol:
WDFY2
WDFY2
Neoplasms
0.030
Biomarker
BEFREE
In conclusion, we have uncovered WDFY2 as a tumor suppressor gene and a new potential biomarker for cancer progression.
28653900
2017
×
Entrez Id:
115825
Gene Symbol:
WDFY2
WDFY2
Primary malignant neoplasm
0.030
AlteredExpression
BEFREE
Overexpression of WDFY2 in prostate cancer cells DU145 and PC-3 led to the suppression of cancer cell migration and colony formation.
28653900
2017
×
Entrez Id:
115825
Gene Symbol:
WDFY2
WDFY2
Malignant Neoplasms
0.030
Biomarker
BEFREE
CDKN2D-WDFY2 is a cancer -specific fusion gene recurrent in high-grade serous ovarian carcinoma.
24675677
2014
×
Entrez Id:
115825
Gene Symbol:
WDFY2
WDFY2
Neoplasms
0.030
GeneticVariation
BEFREE
The genomic breakpoint was identified in intron 1 of CDKN2D and intron 2 of WDFY2 in patient tumor , providing direct evidence that this is a fusion gene.
24675677
2014
×
Entrez Id:
115825
Gene Symbol:
WDFY2
WDFY2
Primary malignant neoplasm
0.030
Biomarker
BEFREE
CDKN2D-WDFY2 is a cancer -specific fusion gene recurrent in high-grade serous ovarian carcinoma.
24675677
2014
×
Entrez Id:
115825
Gene Symbol:
WDFY2
WDFY2
Malignant neoplasm of prostate
0.020
Biomarker
BEFREE
WDFY2 is frequently lost in metastatic cancers, most predominantly in ovarian and prostate cancer .
31253801
2019
×
Entrez Id:
115825
Gene Symbol:
WDFY2
WDFY2
Prostate carcinoma
0.020
Biomarker
BEFREE
WDFY2 is frequently lost in metastatic cancers, most predominantly in ovarian and prostate cancer .
31253801
2019
×
Entrez Id:
115825
Gene Symbol:
WDFY2
WDFY2
Malignant neoplasm of prostate
0.020
AlteredExpression
BEFREE
Overexpression of WDFY2 in prostate cancer cells DU145 and PC-3 led to the suppression of cancer cell migration and colony formation.
28653900
2017
×
Entrez Id:
115825
Gene Symbol:
WDFY2
WDFY2
Carcinogenesis
0.020
Biomarker
BEFREE
WDFY2 , which is found to be a cancer-specific fusion gene with CDKN2D in ovarian cancer, is a new gene with unknown function in carcinogenesis .
28653900
2017
×
Entrez Id:
115825
Gene Symbol:
WDFY2
WDFY2
Prostate carcinoma
0.020
AlteredExpression
BEFREE
Overexpression of WDFY2 in prostate cancer cells DU145 and PC-3 led to the suppression of cancer cell migration and colony formation.
28653900
2017
×
Entrez Id:
115825
Gene Symbol:
WDFY2
WDFY2
Malignant neoplasm of ovary
0.020
Biomarker
BEFREE
WDFY2 , which is found to be a cancer-specific fusion gene with CDKN2D in ovarian cancer , is a new gene with unknown function in carcinogenesis.
28653900
2017
×
Entrez Id:
115825
Gene Symbol:
WDFY2
WDFY2
Carcinoma, Ovarian Epithelial
0.020
Biomarker
BEFREE
WDFY2 , which is found to be a cancer-specific fusion gene with CDKN2D in ovarian cancer , is a new gene with unknown function in carcinogenesis.
28653900
2017
×
Entrez Id:
115825
Gene Symbol:
WDFY2
WDFY2
Carcinogenesis
0.020
AlteredExpression
BEFREE
The expression of short WDFY2 protein in transfected cells appears to alter the PI3K/AKT pathway that is known to play a role in oncogenesis .
24675677
2014
×
Entrez Id:
115825
Gene Symbol:
WDFY2
WDFY2
Malignant neoplasm of ovary
0.020
Biomarker
BEFREE
CDKN2D-WDFY2 fusion could be an important molecular signature for understanding and classifying sub-lineages among heterogeneous high-grade serous ovarian carcinomas .
24675677
2014
×
Entrez Id:
115825
Gene Symbol:
WDFY2
WDFY2
Carcinoma, Ovarian Epithelial
0.020
Biomarker
BEFREE
CDKN2D-WDFY2 is a cancer-specific fusion gene recurrent in high-grade serous ovarian carcinoma .
24675677
2014
×
Entrez Id:
115825
Gene Symbol:
WDFY2
WDFY2
Tumor Cell Invasion
0.010
Biomarker
BEFREE
WDFY2 restrains matrix metalloproteinase secretion and cell invasion by controlling VAMP3-dependent recycling.
31253801
2019
×
Entrez Id:
115825
Gene Symbol:
WDFY2
WDFY2
Prostatic Neoplasms
0.010
AlteredExpression
BEFREE
Our results showed that WDFY2 had lower expression level in prostate tumors than in normal tissues.
28653900
2017
×
Entrez Id:
115825
Gene Symbol:
WDFY2
WDFY2
Tumor Progression
0.010
Biomarker
BEFREE
In conclusion, we have uncovered WDFY2 as a tumor suppressor gene and a new potential biomarker for cancer progression .
28653900
2017
×
Entrez Id:
115825
Gene Symbol:
WDFY2
WDFY2
ovarian neoplasm
0.010
Biomarker
BEFREE
WDFY2 , which is found to be a cancer-specific fusion gene with CDKN2D in ovarian cancer , is a new gene with unknown function in carcinogenesis.
28653900
2017
×
Entrez Id:
115825
Gene Symbol:
WDFY2
WDFY2
Ovarian Carcinoma
0.010
Biomarker
BEFREE
CDKN2D-WDFY2 is a cancer-specific fusion gene recurrent in high-grade serous ovarian carcinoma .
24675677
2014