Source: GWASCAT

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.700 GeneticVariation GWASCAT Discovery of common and rare genetic risk variants for colorectal cancer. 30510241

2019

Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip
0.440 GeneticVariation GWASCAT Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data. 30664745

2019

Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
CUI: C0029410
Disease: Osteoarthritis of hip
Osteoarthritis of hip
0.440 GeneticVariation GWASCAT Meta-analysis of Icelandic and UK data sets identifies missense variants in SMO, IL11, COL11A1 and 13 more new loci associated with osteoarthritis. 30374069

2018

Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
CUI: C0010346
Disease: Crohn Disease
Crohn Disease
0.430 GeneticVariation GWASCAT Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease. 28067908

2017

Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
CUI: C0010346
Disease: Crohn Disease
Crohn Disease
0.430 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007

2016

Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
CUI: C0010346
Disease: Crohn Disease
Crohn Disease
0.430 GeneticVariation GWASCAT Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases. 26301688

2015

Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
CUI: C0010346
Disease: Crohn Disease
Crohn Disease
0.430 GeneticVariation GWASCAT Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. 26192919

2015

Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
CUI: C0010346
Disease: Crohn Disease
Crohn Disease
0.430 GeneticVariation GWASCAT Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. 21102463

2010

Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.400 GeneticVariation GWASCAT Discovery of common and rare genetic risk variants for colorectal cancer. 30510241

2019

Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
CUI: C3495559
Disease: Juvenile arthritis
Juvenile arthritis
0.400 GeneticVariation GWASCAT Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases. 26301688

2015

Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
CUI: C0004096
Disease: Asthma
Asthma
0.160 GeneticVariation GWASCAT Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct. 30929738

2019

Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
CUI: C0004096
Disease: Asthma
Asthma
0.160 GeneticVariation GWASCAT Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis. 31619474

2019

Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
CUI: C0004096
Disease: Asthma
Asthma
0.160 GeneticVariation GWASCAT Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study. 30552067

2019

Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.160 GeneticVariation GWASCAT Discovery of common and rare genetic risk variants for colorectal cancer. 30510241

2019

Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
CUI: C0004096
Disease: Asthma
Asthma
0.160 GeneticVariation GWASCAT Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks. 29273806

2018

Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
CUI: C0004096
Disease: Asthma
Asthma
0.160 GeneticVariation GWASCAT A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases. 29785011

2018

Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
CUI: C0004096
Disease: Asthma
Asthma
0.160 GeneticVariation GWASCAT Detection and interpretation of shared genetic influences on 42 human traits. 27182965

2016

Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.160 GeneticVariation GWASCAT A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease. 26343387

2015

Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
CUI: C0004096
Disease: Asthma
Asthma
0.160 GeneticVariation GWASCAT Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype. 24388013

2014

Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
CUI: C0004096
Disease: Asthma
Asthma
0.160 GeneticVariation GWASCAT A large-scale, consortium-based genomewide association study of asthma. 20860503

2010

Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.140 GeneticVariation GWASCAT Genomewide association analysis of coronary artery disease. 17634449

2007

Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.130 GeneticVariation GWASCAT Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease. 29212778

2018

Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis
0.130 GeneticVariation GWASCAT Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease. 28067908

2017

Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
CUI: C0021390
Disease: Inflammatory Bowel Diseases
Inflammatory Bowel Diseases
0.130 GeneticVariation GWASCAT Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease. 28067908

2017

Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease
0.130 GeneticVariation GWASCAT Association analyses based on false discovery rate implicate new loci for coronary artery disease. 28714975

2017