Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5580
Gene Symbol: PRKCD
PRKCD
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.500 Biomarker CTD_human Correction of vascular hypercontractility in spontaneously hypertensive rats using shRNAs-induced delta protein kinase C gene silencing. 23973649

2013
Entrez Id: 5580
Gene Symbol: PRKCD
PRKCD
CUI: C3809928
Disease: AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME, TYPE III
AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME, TYPE III 		0.500 Biomarker GENOMICS_ENGLAND Loss-of-function of the protein kinase C δ (PKCδ) causes a B-cell lymphoproliferative syndrome in humans. 23430113

2013
Entrez Id: 5580
Gene Symbol: PRKCD
PRKCD
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental 		0.500 Biomarker CTD_human Myocardial effects of ethanol consumption in the rat with streptozotocin-induced diabetes. 12198386

2002
Entrez Id: 5580
Gene Symbol: PRKCD
PRKCD
CUI: C3809928
Disease: AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME, TYPE III
AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME, TYPE III 		0.500 Biomarker CTD_human

Entrez Id: 5580
Gene Symbol: PRKCD
PRKCD
CUI: C0036572
Disease: Seizures
Seizures 		0.410 Biomarker CTD_human Protein kinase Cδ mediates trimethyltin-induced neurotoxicity in mice in vivo via inhibition of glutathione defense mechanism. 25895139

2016
Entrez Id: 5580
Gene Symbol: PRKCD
PRKCD
CUI: C0400966
Disease: Non-alcoholic Fatty Liver Disease
Non-alcoholic Fatty Liver Disease 		0.310 Biomarker CTD_human Misregulation of membrane trafficking processes in human nonalcoholic steatohepatitis. 29341352

2018
Entrez Id: 5580
Gene Symbol: PRKCD
PRKCD
CUI: C4048158
Disease: Convulsions
Convulsions 		0.310 Biomarker CTD_human Protein kinase Cδ mediates trimethyltin-induced neurotoxicity in mice in vivo via inhibition of glutathione defense mechanism. 25895139

2016
Entrez Id: 5580
Gene Symbol: PRKCD
PRKCD
CUI: C1328840
Disease: Autoimmune Lymphoproliferative Syndrome
Autoimmune Lymphoproliferative Syndrome 		0.310 GermlineCausalMutation ORPHANET Loss-of-function of the protein kinase C δ (PKCδ) causes a B-cell lymphoproliferative syndrome in humans. 23430113

2013
Entrez Id: 5580
Gene Symbol: PRKCD
PRKCD
CUI: C0019193
Disease: Hepatitis, Toxic
Hepatitis, Toxic 		0.300 Therapeutic CTD_human Protein kinase Cδ knockout mice are protected from cocaine-induced hepatotoxicity. 30393195

2019
Entrez Id: 5580
Gene Symbol: PRKCD
PRKCD
CUI: C0020672
Disease: Hypothermia, natural
Hypothermia, natural 		0.300 Therapeutic CTD_human 5-HT1A receptor agonist 8-OH-DPAT induces serotonergic behaviors in mice via interaction between PKCδ and p47phox. 30366073

2019
Entrez Id: 5580
Gene Symbol: PRKCD
PRKCD
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease 		0.300 Therapeutic CTD_human Protein kinase Cδ knockout mice are protected from cocaine-induced hepatotoxicity. 30393195

2019
Entrez Id: 5580
Gene Symbol: PRKCD
PRKCD
CUI: C1262760
Disease: Hepatitis, Drug-Induced
Hepatitis, Drug-Induced 		0.300 Therapeutic CTD_human Protein kinase Cδ knockout mice are protected from cocaine-induced hepatotoxicity. 30393195

2019
Entrez Id: 5580
Gene Symbol: PRKCD
PRKCD
CUI: C3658290
Disease: Drug-Induced Acute Liver Injury
Drug-Induced Acute Liver Injury 		0.300 Therapeutic CTD_human Protein kinase Cδ knockout mice are protected from cocaine-induced hepatotoxicity. 30393195

2019
Entrez Id: 5580
Gene Symbol: PRKCD
PRKCD
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		0.300 Therapeutic CTD_human Protein kinase Cδ knockout mice are protected from cocaine-induced hepatotoxicity. 30393195

2019
Entrez Id: 5580
Gene Symbol: PRKCD
PRKCD
CUI: C4279912
Disease: Chemically-Induced Liver Toxicity
Chemically-Induced Liver Toxicity 		0.300 Therapeutic CTD_human Protein kinase Cδ knockout mice are protected from cocaine-induced hepatotoxicity. 30393195

2019
Entrez Id: 5580
Gene Symbol: PRKCD
PRKCD
CUI: C3241937
Disease: Nonalcoholic Steatohepatitis
Nonalcoholic Steatohepatitis 		0.300 Biomarker CTD_human Misregulation of membrane trafficking processes in human nonalcoholic steatohepatitis. 29341352

2018
Entrez Id: 5580
Gene Symbol: PRKCD
PRKCD
CUI: C0022333
Disease: Jacksonian Seizure
Jacksonian Seizure 		0.300 Biomarker CTD_human Protein kinase Cδ mediates trimethyltin-induced neurotoxicity in mice in vivo via inhibition of glutathione defense mechanism. 25895139

2016
Entrez Id: 5580
Gene Symbol: PRKCD
PRKCD
CUI: C0149958
Disease: Complex partial seizures
Complex partial seizures 		0.300 Biomarker CTD_human Protein kinase Cδ mediates trimethyltin-induced neurotoxicity in mice in vivo via inhibition of glutathione defense mechanism. 25895139

2016
Entrez Id: 5580
Gene Symbol: PRKCD
PRKCD
CUI: C0234533
Disease: Generalized seizures
Generalized seizures 		0.300 Biomarker CTD_human Protein kinase Cδ mediates trimethyltin-induced neurotoxicity in mice in vivo via inhibition of glutathione defense mechanism. 25895139

2016
Entrez Id: 5580
Gene Symbol: PRKCD
PRKCD
CUI: C0234535
Disease: Clonic Seizures
Clonic Seizures 		0.300 Biomarker CTD_human Protein kinase Cδ mediates trimethyltin-induced neurotoxicity in mice in vivo via inhibition of glutathione defense mechanism. 25895139

2016
Entrez Id: 5580
Gene Symbol: PRKCD
PRKCD
CUI: C0270824
Disease: Visual seizure
Visual seizure 		0.300 Biomarker CTD_human Protein kinase Cδ mediates trimethyltin-induced neurotoxicity in mice in vivo via inhibition of glutathione defense mechanism. 25895139

2016
Entrez Id: 5580
Gene Symbol: PRKCD
PRKCD
CUI: C0270844
Disease: Tonic Seizures
Tonic Seizures 		0.300 Biomarker CTD_human Protein kinase Cδ mediates trimethyltin-induced neurotoxicity in mice in vivo via inhibition of glutathione defense mechanism. 25895139

2016
Entrez Id: 5580
Gene Symbol: PRKCD
PRKCD
CUI: C0270846
Disease: Epileptic drop attack
Epileptic drop attack 		0.300 Biomarker CTD_human Protein kinase Cδ mediates trimethyltin-induced neurotoxicity in mice in vivo via inhibition of glutathione defense mechanism. 25895139

2016
Entrez Id: 5580
Gene Symbol: PRKCD
PRKCD
CUI: C0422850
Disease: Seizures, Somatosensory
Seizures, Somatosensory 		0.300 Biomarker CTD_human Protein kinase Cδ mediates trimethyltin-induced neurotoxicity in mice in vivo via inhibition of glutathione defense mechanism. 25895139

2016
Entrez Id: 5580
Gene Symbol: PRKCD
PRKCD
CUI: C0422852
Disease: Seizures, Auditory
Seizures, Auditory 		0.300 Biomarker CTD_human Protein kinase Cδ mediates trimethyltin-induced neurotoxicity in mice in vivo via inhibition of glutathione defense mechanism. 25895139

2016